Hauth E A, Umutlu L, Libera H, Kimmig R, Forsting M
Institut für diagnostische und interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen.
Rofo. 2009 Jun;181(6):543-8. doi: 10.1055/s-0028-1109179. Epub 2009 Feb 24.
MRI evaluation of parameters of the ovaries for the diagnosis of polycystic ovaries in patients with polycystic ovary syndrome (PCOS).
An MRI of the pelvis was performed in 51 patients with PCOS and 50 healthy volunteers. The volume and maximum diameter of the bigger ovary, the number of follicles, and the maximum diameter and volume of the biggest follicle of the bigger ovary were determined in relation to patient age and were statistically compared. ROC analysis was performed to evaluate the prognostic quality of the parameters of the ovaries regarding the diagnosis of PCOS.
In a cohort aged 21 - 30 a significant difference between patients with PCOS and healthy volunteers was able to be determined for all 5 parameters (p < 0.001). In the cohort aged 31 - 40 neither one of the parameters showed a significant difference. In the group of 21 - 30 year-olds the AUC was significantly different from 0.5 in all parameters. The maximum diameter, the volume and the number of follicles of the bigger ovary presented the highest AUC. The parameters needed to diagnose PCOS in MRI in a group of women aged 21 - 30 are a maximum diameter of an ovary of 30 mm, an ovarian volume of 5.6 cm(3) and at least 12 follicles. In regard to these parameters a diagnostic sensitivity of 90.32%, 90.32 % und 80.65% and a specificity of 68.42%. 63.16% und 86.42% can be reached.
In the cohort aged 21 - 30 PCOS can be diagnosed in MRI with high diagnostic sensitivity.
通过磁共振成像(MRI)评估卵巢参数以诊断多囊卵巢综合征(PCOS)患者的多囊卵巢。
对51例PCOS患者和50名健康志愿者进行盆腔MRI检查。测定较大卵巢的体积、最大直径、卵泡数量以及较大卵巢中最大卵泡的最大直径和体积,并与患者年龄相关联,进行统计学比较。采用ROC分析评估卵巢参数对PCOS诊断的预后质量。
在21 - 30岁的队列中,所有5个参数在PCOS患者和健康志愿者之间均能确定存在显著差异(p < 0.001)。在31 - 40岁的队列中,没有一个参数显示出显著差异。在21 - 30岁的组中,所有参数的AUC均显著不同于0.5。较大卵巢的最大直径、体积和卵泡数量的AUC最高。在21 - 30岁的女性组中,MRI诊断PCOS所需的参数为卵巢最大直径30 mm、卵巢体积5.6 cm³和至少12个卵泡。就这些参数而言,诊断敏感性分别为90.32%、90.32%和80.65%,特异性分别为68.42%、63.16%和86.42%。
在21 - 30岁的队列中,MRI能够以较高的诊断敏感性诊断PCOS。