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[全髋关节置换术前无症状血栓栓塞性静脉疾病——何时风险重要?]

[Asymptomatic thrombo-embolic venous disease before total hip replacement--when the risk is important?].

作者信息

Jabłoński Mirosław, Turzańska Karolina, Gorzelak Mieczysław, Posturzyńska Agnieszka, Wójcik Beata, Pluta Ryszard

机构信息

Kliniki Ortopedii i Rehabilitacji, Uniwersytet Medyczny w Lublinie.

出版信息

Chir Narzadow Ruchu Ortop Pol. 2008 Nov-Dec;73(6):381-5.

Abstract

In spite of widely applied prophylaxis against thrombo-embolic venous disease its future complications still present important clinical issue. According to rough statistics this disease occurs in 71/100 000 persons per year and reveals in 1/3 as pulmonary embolism and in 2/3 as a pure thrombotic venous disease. Massive pulmonary embolism is at present a major cause of death in hospitalized subjects. In the USA mortality due to diagnosed pulmonary embolism is reported as approximately 25 000 cases per year. The aim of this paper is to draw attention to the asymptomatic cases of the thrombotic venous disease in the patients before hip arthroplasty. A retrospective clinical analysis of 210 total hip replacements (years 2005-2008) was performed. Standard perioperative routine antithrombotic prophylaxis with low-molecule heparins was introduced in each case. Special attention was paid to the occurrence of the risk factors or the presence of venous thrombosis in the lower extremities perioperatively. In the analyzed group preoperative ultrasound revealed in 5 (2.38%) cases asymptomatic venous thrombi reaching above the knee region and this was the cause of postponing of the procedure. In the early postoperative period pulmonary embolism was evidenced in 4 cases (1.9%). The authors suggested that preoperative ultrasound investigation of lower extremities venous system is important issue together with the assessment of d-dimers in the blood in all patients admitted to total hip arthroplasty. In any suspicion of the pulmonary embolism in these patients an angio-CT should be performed as an emergency.

摘要

尽管针对血栓栓塞性静脉疾病的预防措施已广泛应用,但其未来并发症仍是重要的临床问题。据粗略统计,该疾病每年的发病率为每10万人中有71例,其中1/3表现为肺栓塞,2/3表现为单纯的血栓性静脉疾病。目前,大面积肺栓塞是住院患者死亡的主要原因。在美国,据报道每年因确诊肺栓塞导致的死亡病例约为25000例。本文旨在引起人们对髋关节置换术前患者血栓性静脉疾病无症状病例的关注。对210例全髋关节置换术(2005 - 2008年)进行了回顾性临床分析。每例患者均采用标准的围手术期常规低分子肝素抗血栓预防措施。特别关注围手术期下肢危险因素的出现或静脉血栓的存在。在分析组中,术前超声检查发现5例(2.38%)患者存在无症状静脉血栓,血栓延伸至膝关节以上区域,这是手术推迟的原因。术后早期有4例(1.9%)患者证实发生了肺栓塞。作者建议,对于所有接受全髋关节置换术的患者,术前对下肢静脉系统进行超声检查以及评估血液中的D - 二聚体是重要的事项。对于这些患者,一旦怀疑有肺栓塞,应紧急进行血管CT检查。

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