Lettieri Christopher J, Shah Anita A, Greenburg David L
Pulmonary and Critical Care Medicine, Walter Reed Army Medical Center, Washington, DC, USA.
Crit Care Med. 2009 Apr;37(4):1256-60. doi: 10.1097/CCM.0b013e31819c167f.
Intensivist-directed intensive care units (ICUs) have been shown to improve clinical outcomes. Numerous barriers exist that limit hospitals adopting this practice. We sought to show this staffing model can be implemented in an austere environment with limited resources resulting in improved outcomes.
We conducted a retrospective observational cohort study of consecutive adult patients admitted to the ICU between March 2004 and January 2007.
This study was conducted in an ICU in a U.S. Army Combat Support Hospital deployed to Afghanistan.
North Atlantic Trade Organization members (U.S. military service members, American civilian contractors, members of the North Atlantic Trade Organization Coalition International Security Assistance Force), members of the Afghanistan National Army and National Police, and local Afghani nationals were included in the study. Both traumatic injuries and medical illnesses were treated.
During the observation period, the ICU was converted from an open model to an intensivist-directed model.
Outcomes compared between the two models included ICU and hospital mortality, duration of mechanical ventilation, and ventilator-associated pneumonia rates. During the observation period, there were 2740 admissions, 965 of which were initially admitted to the ICU. We found significant reductions in ICU mortality (6.6% vs. 4.0%, p < 0.001), duration of mechanical ventilation (4.7 +/- 3.9 days vs. 3.1 +/- 2.7 days, p < 0.001), and rates of ventilator-associated pneumonia (42.5% vs. 8.0%; p < 0.001).
Transition to an intensivist-directed ICU in an Army Combat Support Hospital improved outcomes among ICU patients. This study demonstrates the feasibility of using this model in an austere, combat environment.
有研究表明,由重症医学专家主导的重症监护病房(ICU)可改善临床结局。然而,存在诸多障碍限制医院采用这种模式。我们试图证明,在资源有限的严峻环境中也可实施这种人员配置模式,并能改善结局。
我们对2004年3月至2007年1月期间连续入住ICU的成年患者进行了一项回顾性观察队列研究。
本研究在部署到阿富汗的一家美国陆军战斗支援医院的ICU进行。
北大西洋公约组织成员(美国军人、美国文职承包商、北大西洋公约组织联盟国际安全援助部队成员)、阿富汗国民军和国家警察成员以及当地阿富汗国民被纳入研究。研究涵盖创伤性损伤和内科疾病的治疗。
在观察期内,ICU从开放模式转变为由重症医学专家主导的模式。
比较两种模式下的结局指标包括ICU死亡率、医院死亡率、机械通气时间和呼吸机相关性肺炎发生率。在观察期内,共有2740例入院患者,其中965例最初入住ICU。我们发现ICU死亡率显著降低(6.6%对4.0%,p<0.001)、机械通气时间显著缩短(4.7±3.9天对3.1±2.7天,p<0.001)以及呼吸机相关性肺炎发生率显著降低(42.5%对8.0%;p<0.001)。
美国陆军战斗支援医院向由重症医学专家主导的ICU转变改善了ICU患者的结局。本研究证明了在严峻的战斗环境中采用这种模式的可行性。