甲状旁腺切除术后短暂性术后甲状腺毒症
Transient post-operative thyrotoxicosis after parathyroidectomy.
作者信息
Rudofsky Gottfried, Grafe Ingo A, Metzner Cornelia, Leowardi Christina, Fohr Berthold
机构信息
Department of Endocrinology and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany.
出版信息
Med Sci Monit. 2009 Mar;15(3):CS41-3.
BACKGROUND
Secondary and tertiary hyperparathyroidism are features of chronic renal disease. Although pharmacological options are available, parathyroid surgery remains the treatment of choice in these patients with worsening renal osteodystrophy or hypercalcemia. The development of thyrotoxicosis after parathyroid surgery in these patients has been rarely reported.
CASE REPORT
We report a 33 years old woman who developed transient symptomatic thyrotoxicosis following parathyroid surgery for tertiary hyperparathyroidism. Laboratory and imaging studies were consistent with postoperative hyperthyroidism due to thyroiditis.
CONCLUSIONS
Transient hyperthyroidism may occur after parathyroidectomy presumably due to a traumatic thyroiditis as a result of manipulation of the thyroid gland during surgery. As it is transient, thyrostatic therapy is not indicated but patients may require short-term treatment with beta-blockers for symptomatic relief.
背景
继发性和三发性甲状旁腺功能亢进是慢性肾病的特征。尽管有药物治疗选择，但对于这些肾性骨营养不良或高钙血症病情恶化的患者，甲状旁腺手术仍是首选治疗方法。这些患者甲状旁腺手术后发生甲状腺毒症的情况鲜有报道。
病例报告
我们报告一名33岁女性，因三发性甲状旁腺功能亢进接受甲状旁腺手术后出现短暂性症状性甲状腺毒症。实验室和影像学检查结果与术后甲状腺炎所致的甲状腺功能亢进相符。
结论
甲状旁腺切除术后可能会发生短暂性甲状腺功能亢进，推测是由于手术过程中甲状腺受到操作导致创伤性甲状腺炎。由于其为短暂性，无需使用抗甲状腺药物治疗，但患者可能需要短期使用β受体阻滞剂进行对症治疗。
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