Díez M R, De la Rosa G, Pascual R, Girón C, Arteta M
Hospital Universitario de Getafe, Madrid, España.
Arch Soc Esp Oftalmol. 2009 Feb;84(2):85-9. doi: 10.4321/s0365-66912009000200006.
To present the outcomes of prophylaxis of postoperative endophthalmitis following cataract surgery with intracameral Cefuroxime.
A retrospective study was done on 4281 eyes that underwent cataract surgery from October 2003 to September 2008. All patients underwent phacoemulsification cataract surgery. All cases received an injection of 0.1 ml intracameral Cefuroxime (1 mg) at the end of surgery except those patients allergic to penicillin and cephalosporin until September 2007 and thereafter only those with demonstrated allergy to cefuroxime.
The rate of postoperative endophthalmitis was 0.11% (5 cases). Four of them had a positive culture. We found no evidence of clinical ocular toxicity.
Intracameral cefuroxime works very well for reducing the incidence of postoperative endophthalmitis. It appears safe to use and is easy to prepare.
介绍使用前房内注射头孢呋辛预防白内障手术后眼内炎的效果。
对2003年10月至2008年9月期间接受白内障手术的4281只眼进行回顾性研究。所有患者均接受了超声乳化白内障手术。除对青霉素和头孢菌素过敏的患者（2007年9月前）以及之后仅对头孢呋辛过敏的患者外，所有病例在手术结束时均在前房内注射0.1 ml头孢呋辛（1 mg）。
术后眼内炎发生率为0.11%（5例）。其中4例培养结果呈阳性。未发现临床眼毒性证据。
前房内注射头孢呋辛在降低术后眼内炎发生率方面效果良好。使用似乎安全且易于配制。
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