Caltabiano R, Lanzafame S
Department G.F. Ingrassia, Section of Anatomic Pathology, University of Catania, Italy.
Pathologica. 2008 Oct;100(5):420-3.
We describe the case of an 18-year-old girl with an oligodendroglioma arising in an immature ovarian teratoma. The oligodendroglioma, which closely involved the cystic teratoma, was moderately cellular, composed of monomorphic cells with uniform round nuclei and perinuclear halos with a characteristic "fried-egg" appearance. Rare microcalcifications and a dense network of branching capillaries with a chicken-wire appearance were also observed. By immunohistochemistry, tumour cells showed positivity for S-100, but were negative for GFAP, synaptophysin and neuro-specific enolase. The patient is free of disease on follow-up examination at 24 months.
我们描述了一例18岁女孩的病例,其少突胶质细胞瘤发生于未成熟卵巢畸胎瘤中。少突胶质细胞瘤紧密累及囊性畸胎瘤,细胞中度密集,由具有均匀圆形核和核周晕的单形细胞组成,呈现特征性的“煎蛋”外观。还观察到罕见的微钙化以及呈铁丝网外观的密集分支毛细血管网络。免疫组织化学显示,肿瘤细胞S-100呈阳性,但胶质纤维酸性蛋白(GFAP)、突触素和神经特异性烯醇化酶呈阴性。该患者在24个月的随访检查中无疾病复发。