脊柱疼痛与颞下颌关节紊乱之间是否存在剂量反应关系?

Does a dose-response relation exist between spinal pain and temporomandibular disorders?

作者信息

Wiesinger Birgitta, Malker Hans, Englund Erling, Wänman Anders

机构信息

Department of Research and Development, Sundsvall Hospital, 85186 Sundsvall, Sweden.

出版信息

BMC Musculoskelet Disord. 2009 Mar 2;10:28. doi: 10.1186/1471-2474-10-28.

Abstract

BACKGROUND

The aim of this study was to test whether a reciprocal dose-response relation exists between frequency/severity of spinal pain and temporomandibular disorders (TMD).

METHODS

A total of 616 subjects with varying severity of spinal pain or no spinal pain completed a questionnaire focusing on symptoms in the jaw, head and spinal region. A subset of the population (n = 266) were sampled regardless of presence or absence of spinal pain. We used two different designs, one with frequency/severity of spinal pain, and the other, with frequency/severity of TMD symptoms as independent variable. All 616 participants were allocated to four groups, one control group without spinal pain and three spinal pain groups. The subjects in the subset were allocated to one control group without TMD symptoms and three TMD groups. Odds ratios (ORs) were calculated for presence of frequent TMD symptoms in the separate spinal pain groups as well as for frequent spinal pain in the separate TMD groups.

RESULTS

The analysis showed increasing ORs for TMD with increasing frequency/severity of spinal pain. We also found increasing ORs for spinal pain with increasing frequency/severity of TMD symptoms.

CONCLUSION

This study shows a reciprocal dose-response-like relationship between spinal pain and TMD. The results indicate that these two conditions may share common risk factors or that they may influence each other. Studies on the temporal sequence between spinal pain and TMD are warranted.

摘要

背景

本研究旨在测试脊柱疼痛的频率/严重程度与颞下颌关节紊乱病(TMD)之间是否存在相互的剂量反应关系。

方法

共有616名脊柱疼痛程度不同或无脊柱疼痛的受试者完成了一份聚焦于颌部、头部和脊柱区域症状的问卷。对该人群的一个子集(n = 266)进行抽样,无论其是否存在脊柱疼痛。我们采用了两种不同的设计,一种以脊柱疼痛的频率/严重程度作为自变量,另一种以TMD症状的频率/严重程度作为自变量。所有616名参与者被分为四组,一组为无脊柱疼痛的对照组,三组为脊柱疼痛组。子集中的受试者被分为一组无TMD症状的对照组和三组TMD组。计算了各脊柱疼痛组中频繁出现TMD症状的比值比(OR)以及各TMD组中频繁出现脊柱疼痛的比值比。

结果

分析显示,随着脊柱疼痛频率/严重程度的增加,TMD的OR升高。我们还发现,随着TMD症状频率/严重程度的增加,脊柱疼痛的OR也升高。

结论

本研究显示了脊柱疼痛与TMD之间类似相互剂量反应的关系。结果表明,这两种情况可能有共同的风险因素,或者它们可能相互影响。有必要对脊柱疼痛和TMD之间的时间顺序进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3d2/2653030/d38b1b5e79d1/1471-2474-10-28-1.jpg

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