人口统计学和临床病理因素对伊朗早期胃癌预后的影响。
Effect of demographic and clinicopathologic factors on prognosis of early gastric cancer in Iran.
作者信息
Moghimi-Dehkordi Bijan, Safaee Azadeh, Pourhoseingholi Mohamad Amin, Zali Mohammad Reza
机构信息
Research Center for Gastroenterology and Liver Diseases, Shaheed Beheshti University, MC, Tehran, Iran. b_moghimi_de@ yahoo.com
出版信息
Asian Pac J Cancer Prev. 2008 Oct-Dec;9(4):585-8.
BACKGROUND
The aim of this study was to estimate some prognostic factors that affect on overall survival of patients with early gastric cancer.
METHODS
A retrospective study had been done on patients diagnosed with early gastric cancer who registered in cancer registry center, Tehran, Iran, between December 21, 2001 and December 21, 2006 and all patients were followed by telephone contacts. The Kaplan-Meier method was performed to describe survival curves and log-rank test to compare the survival rate in subgroups. Cox regression was used to determine the prognosis factors.
RESULTS
The mean age was 57.9 years and 72.6% of patients were male. Tumor size (>35 mm) and lymph node metastasis were established as significant factors for survival of patients with EGC in both univariate and multivariate analysis.
CONCLUSION
The findings of this study indicate that lymph node metastasis and tumor size are the most independent prognostic factors in these patients.
背景
本研究旨在评估一些影响早期胃癌患者总生存期的预后因素。
方法
对2001年12月21日至2006年12月21日期间在伊朗德黑兰癌症登记中心登记的早期胃癌患者进行了一项回顾性研究，所有患者均通过电话随访。采用Kaplan-Meier方法描述生存曲线，采用对数秩检验比较亚组生存率。采用Cox回归确定预后因素。
结果
平均年龄为57.9岁，72.6%的患者为男性。在单因素和多因素分析中，肿瘤大小（>35mm）和淋巴结转移均被确定为早期胃癌患者生存的重要因素。
结论
本研究结果表明，淋巴结转移和肿瘤大小是这些患者最独立的预后因素。
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