Hayden Melanie G, Gephart Rosanne, Kalanithi Paul, Chou Dean
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Road, Stanford, California 94305, USA.
J Clin Neurosci. 2009 May;16(5):611-3. doi: 10.1016/j.jocn.2008.05.032. Epub 2009 Mar 3.
The hormonal and hemodynamic effects of pregnancy accelerate the growth of hemangioblastomas in Von Hippel-Lindau syndrome (VHL), leading to increased symptoms and risk to both the mother and fetus. A review of the literature on the treatment of VHL in pregnancy would suggest surgical intervention should be considered with worsening clinical status. Introducing this review is a description of our patient with VHL, who uniquely presented in pregnancy with a cervical hemangioblastoma.
妊娠的激素和血流动力学效应会加速冯·希佩尔-林道综合征(VHL)中血管母细胞瘤的生长,导致母亲和胎儿的症状加重及风险增加。一篇关于妊娠期VHL治疗的文献综述表明,随着临床状况恶化,应考虑手术干预。本文首先介绍了我们的一位VHL患者,她在妊娠期独特地出现了颈部血管母细胞瘤。