Yasugi Akiko, Matsuoka Hiroshi, Otani Hideyuki, Maeda Kazunori, Matsumoto Kazuya, Koda Masaharu, Kawaguchi Koichiro, Harada Kenichi, Yashima Kazuo, Murawaki Yoshikazu, Horie Yasushi
Division of Medicine and Clinical Science, Tottori University, Japan.
Nihon Shokakibyo Gakkai Zasshi. 2009 Mar;106(3):377-82.
A 83-year-old man with a 2-year history of diarrhea was admitted hospital because of increased diarrhea and general fatigue. He had severe dehydration, hyponatremia, hypokalemia and hypochloremia. Abdominal CT showed tumor and fluid in the rectum. Colonoscopy revealed large tumor with a villous structure in the rectum. Low anterior resection was performed. The histopathological diagnosis was adenocarcinoma with villous adenoma. The immunostaining of the tumor revealed positive COX-2 expression. The diarrhea and electrolyte disturbance disappeared after the resection of tumor.
一名83岁男性,有2年腹泻病史,因腹泻加重和全身乏力入院。他有严重脱水、低钠血症、低钾血症和低氯血症。腹部CT显示直肠有肿瘤和积液。结肠镜检查发现直肠有一个具有绒毛状结构的大肿瘤。进行了低位前切除术。组织病理学诊断为腺癌伴绒毛状腺瘤。肿瘤的免疫染色显示COX-2表达阳性。肿瘤切除后腹泻和电解质紊乱消失。