Thomas Laneshia, Bledsoe Jonathan M, Stead Matt, Sandroni Paola, Gorman Deborah, Lee Kendall H
Department of Neurosurgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Curr Neurol Neurosci Rep. 2009 Mar;9(2):120-6. doi: 10.1007/s11910-009-0020-y.
Intractable neuropathic face pain is a syndrome of unremitting severe pain that stems from abnormal nociceptive processing at various levels of the trigeminal system. Treatment of this debilitating condition has long presented a challenge for physicians due to its refractoriness to standard pharmacologic therapies. With few viable treatments, surgical procedures such as motor cortex stimulation (MCS) and deep brain stimulation (DBS) provide additional options. This article reviews the current literature and practices regarding patient selection criteria, potential mechanisms of action, surgical technique, and outcome of patients with neuropathic face pain treated with MCS and DBS.
顽固性神经性面部疼痛是一种持续严重疼痛的综合征,其源于三叉神经系统不同水平的异常伤害性感受处理。由于这种使人衰弱的病症对标准药物治疗具有难治性,长期以来,其治疗一直是医生面临的一项挑战。由于可行的治疗方法很少,诸如运动皮层刺激(MCS)和深部脑刺激(DBS)等外科手术提供了更多选择。本文综述了有关MCS和DBS治疗神经性面部疼痛患者的患者选择标准、潜在作用机制、手术技术及结果的当前文献和实践。