Ross E Victor, Swann Michael, Soon Seaver, Izadpanah Arash, Barnette David, Davenport Scott
Dermatology Division, Scripps Clinic, San Diego, CA 92130, USA.
J Drugs Dermatol. 2009 Mar;8(3):248-52.
Traditional full-face resurfacing has been limited to erbium-doped yttrium aluminium garnet (Er:YAG) and carbon dioxide (CO2) lasers. These devices offer wavelength-specific advantages and disadvantages.
Nine patients were enrolled in a pilot study of a resurfacing system using a 2790-nm erbium:yttrium-scandium-gallium-garnet (Er:YSGG) laser system. Two treatments were carried out 1 month apart over the entire face. Test spots were performed prior to the full-face sessions to determine the optimal fluence for 1-pass laser resurfacing. Biopsies were performed at the time of treatment and at the final follow-up visit one month after the second treatment. Clinical endpoints included changes in pigment dyschromias, wrinkles, and skin tone. All outcomes were graded by blinded observers.
Eight patients completed the 2 treatments. Biopsies showed thermal damage extending as deep as 80 microm below the stratum corneum. Reepithelialization was complete within 4 days. No scarring, post inflammatory hyperpigmentation (PIH), or infections were observed.
A 2790-nm laser can be used for skin rejuvenation with a 4 day recovery window.
传统的全脸皮肤磨削术仅限于掺铒钇铝石榴石(Er:YAG)激光和二氧化碳(CO2)激光。这些设备具有特定波长的优缺点。
9名患者参与了一项使用2790纳米掺铒钇钪镓石榴石(Er:YSGG)激光系统的皮肤磨削系统的初步研究。在整个面部进行了两次间隔1个月的治疗。在全脸治疗前进行测试光斑,以确定单次激光皮肤磨削的最佳能量密度。在治疗时和第二次治疗后1个月的最终随访时进行活检。临床终点包括色素沉着异常、皱纹和肤色的变化。所有结果均由不知情的观察者进行分级。
8名患者完成了2次治疗。活检显示热损伤延伸至角质层以下80微米深处。4天内上皮再生完成。未观察到瘢痕形成、炎症后色素沉着(PIH)或感染。
2790纳米激光可用于皮肤年轻化,恢复窗口期为4天。