Tao L C
Department of Pathology, University of Toronto, Ontario, Canada.
Acta Cytol. 1991 Sep-Oct;35(5):524-8.
A case of rare extracranial metastasis from a recurrent intracranial meningioma is described. Incidentally discovered asymptomatic pulmonary metastases were diagnosed as meningioma by transthoracic fine needle aspiration (FNA) biopsy. The aspirate contained spindle-shaped tumor cells and other forms that seemed to correspond to the fibroblastic, syncytial and angioblastic areas seen in the histologic sections of the primary tumor. Cytomorphologically, metastatic meningioma appears to be sufficiently distinctive to permit its cytologic differentiation from other spindle-cell tumors. Although meningiomas metastasize rarely, this diagnosis should be considered in the interpretation of a transthoracic FNA biopsy of a pulmonary nodule or nodules in a patient with a history of recurrent intracranial meningioma, especially when the aspirate mainly consists of spindle-shaped neoplastic cells.
本文描述了一例复发性颅内脑膜瘤罕见的颅外转移病例。经偶然发现，无症状的肺转移瘤通过经胸细针穿刺抽吸（FNA）活检被诊断为脑膜瘤。吸出物中含有梭形肿瘤细胞及其他形态的细胞，这些细胞似乎与原发肿瘤组织切片中所见的纤维母细胞、合体细胞和成血管细胞区域相对应。在细胞形态学上，转移性脑膜瘤似乎具有足够的特征，能够在细胞学上与其他梭形细胞肿瘤相鉴别。尽管脑膜瘤很少发生转移，但对于有复发性颅内脑膜瘤病史的患者，在解释肺部结节的经胸FNA活检结果时，应考虑到这种诊断，尤其是当吸出物主要由梭形肿瘤细胞组成时。
