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通过[70]富勒烯-γ-环糊精复合物的交换反应,[70]富勒烯直接且短时间内摄取到细胞膜中以及由此产生的光动力活性。

Direct and short-time uptake of [70]fullerene into the cell membrane using an exchange reaction from a [70]fullerene-gamma-cyclodextrin complex and the resulting photodynamic activity.

作者信息

Ikeda Atsushi, Matsumoto Masashi, Akiyama Motofusa, Kikuchi Jun-ichi, Ogawa Takuya, Takeya Tatsuo

机构信息

Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan.

出版信息

Chem Commun (Camb). 2009 Mar 28(12):1547-9. doi: 10.1039/b820768b. Epub 2009 Jan 29.

Abstract

[70]Fullerene (C70) was directly incorporated into the cell membrane using an exchange reaction from a C70-gamma-cyclodextrin (gamma-CDx) complex within 10 min and the incorporated C70 acted as a photodynamic sensitiser for a cancer cell.

摘要

[70]富勒烯(C70)通过与C70-γ-环糊精(γ-CDx)复合物的交换反应在10分钟内直接掺入细胞膜,掺入的C70作为癌细胞的光动力敏化剂。

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