Zaky Sherif S, Hanna Amgad H, Sakr Esa Wael A, Xu Meng, Lober Cheryl, Sessler Daniel I, Gonzalez-Stawinski Gonzalo, Savage Robert M, Bashour C Allen
Anesthesia Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
J Cardiothorac Vasc Anesth. 2009 Aug;23(4):479-83. doi: 10.1053/j.jvca.2008.12.027. Epub 2009 Mar 12.
The primary objective of this study was to analyze perioperative intra-aortic balloon pump (IABP) insertion in patients undergoing cardiac surgery in the authors' institution from 1995 to 2005 and to propose an explanation for changes in use over this period. A secondary objective was to assess patient variables associated with IABP use.
This is a retrospective study including patients who underwent cardiac surgery between 1995 and 2005.
The Cardiothoracic Anesthesia Patient Registry of a single teaching institution was queried to obtain the required information.
Thirty thousand two hundred sixty-nine cardiac surgery patients.
Intra-aortic balloon pump insertion before surgery, after cardiopulmonary bypass, or in the cardiovascular intensive care unit was assessed in patients who underwent isolated coronary artery bypass graft surgery, valve surgery, or both. Select patient variables were analyzed for their association with IABP insertion. Transesophageal echocardiography (TEE) examinations, milrinone use, and mortality rates also were determined.
Among 30,269 cardiac surgery patients, 1,310 (4.32%) underwent IABP insertion. Combined preoperative, intraoperative, and postoperative IABP use decreased from 7.8% in 1995 to 3.0% in 2005. Simultaneously, the intraoperative use of milrinone increased from 4.8% to 8.8% and postoperative use increased from 5.2% to 7.8%. The number of intraoperative TEE examinations more than doubled from approximately 1,700 to 3,500. The overall mortality for patients with preoperative, intraoperative, and postoperative IABP insertion was 12.6%, 17.5%, and 47.7%, respectively.
From 1995 to 2005, preoperative, intraoperative, and postoperative IABP use decreased by approximately 60% in cardiac surgery patients. Simultaneously, the use of TEE and milrinone each doubled. Although a cause-effect relationship cannot be established from the present study's observational data, the trends coincide and may be related.
本研究的主要目的是分析1995年至2005年期间作者所在机构接受心脏手术患者的围手术期主动脉内球囊反搏(IABP)置入情况,并对这一时期使用情况的变化给出解释。次要目的是评估与IABP使用相关的患者变量。
这是一项回顾性研究,纳入了1995年至2005年期间接受心脏手术的患者。
查询了一家单一教学机构的心胸麻醉患者登记数据库以获取所需信息。
3269名心脏手术患者。
对接受单纯冠状动脉旁路移植术、瓣膜手术或两者皆有的患者,评估术前、体外循环后或心血管重症监护病房内的主动脉内球囊反搏置入情况。分析选定的患者变量与IABP置入的相关性。还测定了经食管超声心动图(TEE)检查、米力农使用情况及死亡率。
在3269名心脏手术患者中,1310名(4.32%)接受了IABP置入。术前、术中和术后联合使用IABP的比例从1995年的7.8%降至2005年的3.0%。同时,术中米力农的使用从4.8%增至8.8%,术后使用从5.2%增至7.8%。术中TEE检查的次数从约1700次增加了一倍多,至3500次。术前、术中和术后置入IABP患者的总体死亡率分别为12.6%、17.5%和47.7%。
1995年至2005年期间,心脏手术患者术前、术中和术后IABP的使用减少了约60%。同时,TEE和米力农的使用均增加了一倍。尽管从本研究的观察性数据中无法确立因果关系,但这些趋势一致且可能相关。