Lentle B C, Russell A S, Percy J S, Jackson F I
J Nucl Med. 1977 Jun;18(6):529-33.
Bone scintigraphs obtained with both Technetium-99m polyphosphate and Technetium-99m pyrophosphate have been abnormal at the sacroiliac joints of 44 patients with definite ankylosing spondylitis (AS). Because of the normal registration of the sacroiliac joints on bone scintigraphy, it has been necessary to develop a profile-scan technique to quantify the abnormality that proves to be significantly different from the normal finding. In 17 patients with a strong clinical suspicion of AS but normal radiographs, the sacroiliac joints have frequently been abnormal. This finding is meaningful because there is a common occurence in this group of the histocompatibility antigen HL A-B27, known to be a marker of AS. We also note the frequency of abnormal sacroiliac scinitigrams in 26 patients with rheumatoid arthritis and in a group of other diseases-Crohn's disease, uveitis, psoriasis, ulcerative colitis, and Reiter's disease-all of which share some of the manifestations of AS.
用锝-99m多聚磷酸盐和锝-99m焦磷酸盐进行骨闪烁扫描时，44例确诊强直性脊柱炎（AS）患者的骶髂关节均显示异常。由于骶髂关节在骨闪烁扫描中的正常显像，有必要开发一种轮廓扫描技术来量化这种异常，该异常被证明与正常表现有显著差异。在17例临床高度怀疑AS但X线片正常的患者中，骶髂关节常显示异常。这一发现具有重要意义，因为在这组患者中，组织相容性抗原HLA - B27的出现频率较高，而HLA - B27是AS的一个标志物。我们还注意到26例类风湿关节炎患者以及一组其他疾病（克罗恩病、葡萄膜炎、银屑病、溃疡性结肠炎和赖特综合征）患者的骶髂关节闪烁扫描异常的频率，所有这些疾病都有一些AS的表现。
