Fugate Mark W, Rotellini-Coltvet Lisa, Freischlag Julie A
Johns Hopkins School of Medicine, 720 Rutland Avenue, Ross 759, Baltimore, MD 21205, USA.
Curr Treat Options Cardiovasc Med. 2009 Apr;11(2):176-83. doi: 10.1007/s11936-009-0018-4.
Thoracic outlet syndrome (TOS) is a condition caused by compression of the neurovascular structures leading to the arm passing through the thoracic outlet. There are three distinct types of TOS: neurogenic (95%), venous (4%-5%), and arterial (1%). Treatment algorithms depend on the type of TOS. Although statistically the most common type, neurogenic TOS can often be the most difficult to diagnose and treat. We have good follow-up data indicating that appropriately selected patients benefit from surgical intervention. Arterial and venous TOS often present more urgently with arterial or venous thrombosis. The thrombosis is typically recognized expeditiously by thorough history taking and physical examination, augmented by duplex ultrasonography. The restoration of blood flow, be it venous or arterial, often can be accomplished readily by thrombolysis. The key, however, comes in diagnosing the underlying structural component involved in the development of symptoms. To prevent recurrence, patients must undergo first rib resection and anterior scalenectomy, as well as resection of any rudimentary or cervical ribs. In the case of arterial TOS, the subclavian artery often requires reconstruction as well. Regardless of the type of TOS encountered, proper treatment requires a multidisciplinary approach.
胸廓出口综合征(TOS)是一种由神经血管结构受压引起的疾病,该神经血管结构通向穿过胸廓出口的手臂。TOS有三种不同类型:神经源性(95%)、静脉性(4%-5%)和动脉性(1%)。治疗方案取决于TOS的类型。虽然从统计学角度来看神经源性TOS是最常见的类型,但它往往也是最难诊断和治疗的。我们有良好的随访数据表明,经过适当选择的患者能从手术干预中获益。动脉性和静脉性TOS通常因动脉或静脉血栓形成而表现得更为紧急。通过全面的病史采集和体格检查,结合双功超声检查,通常能迅速识别出血栓形成。无论是静脉还是动脉,恢复血流通常都可以通过溶栓轻易实现。然而,关键在于诊断出导致症状出现的潜在结构成分。为防止复发,患者必须接受第一肋切除术和前斜角肌切除术,以及切除任何残余或颈肋。对于动脉性TOS,锁骨下动脉通常也需要进行重建。无论遇到哪种类型的TOS,恰当的治疗都需要多学科方法。