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[持续性恶性腹水的良好病程]

[Favourable course of persisting malignant ascites].

作者信息

Stange Rainer, Jänsch Annette, Schrag Sabine, Pflugbeil Christine, Schlodder Dietrich, Pandey-Hoffmann Ursula, Uehleke Bernhard

机构信息

Abteilung fur Naturheilkunde, Charité-Universitatsmedizin Berlin, und Immanuel-Krankenhaus Berlin-Wannsee, Königstrasse 63, Berlin, Germany.

出版信息

Forsch Komplementmed. 2009 Feb;16(1):49-53. doi: 10.1159/000191067. Epub 2009 Jan 30.

Abstract

Malignant ascites is a frequent complication in oncological diseases. There are no standard therapies for any primary tumour. We report the case of a woman, aged 49 years at the time of primary diagnosis, who suffered from recurrent ascites resulting from liver metastasis of breast cancer. Based on the literature and former experience of our department, mistletoe extract was repeatedly applied intraperitoneally at the occasion of decompressive punctures. The further course of the disease suggests a significant role of mistletoe in achieved symptom control, which also resulted in a considerable improvement in quality of life. The mistletoe solution was well tolerated. Relevant mechanisms of action in addition to the well-known immunomodulating properties of mistletoe could be direct cytotoxic and adjuvant effects to the concomitantly administered chemotherapy of carboplatin/paclitaxel.

摘要

恶性腹水是肿瘤疾病中常见的并发症。对于任何原发性肿瘤都没有标准的治疗方法。我们报告了一例女性病例,初次诊断时49岁,因乳腺癌肝转移出现复发性腹水。根据文献和我们科室以前的经验,在减压穿刺时反复腹腔内应用槲寄生提取物。疾病的进一步发展表明槲寄生在实现症状控制方面发挥了重要作用,这也显著改善了生活质量。槲寄生溶液耐受性良好。除了槲寄生众所周知的免疫调节特性外,相关的作用机制可能是对同时给予的卡铂/紫杉醇化疗产生直接细胞毒性和辅助作用。

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