Berlin Fred S
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21202, USA.
J Am Acad Psychiatry Law. 2009;37(1):59-62.
Androgen deprivation treatment (ADT) significantly lowers testosterone. That, in turn, can decrease sexual drive, facilitating better self-control and lower recidivism rates among sexually disordered offenders. Potential side effects can include: decreases in bone density; development of a metabolic syndrome involving weight gain, accompanied by changes in glucose and lipid metabolism; and rarely, depression. In the presence of a proper treatment protocol designed either to prevent or to minimize side effects, particularly the development of osteoporosis, the risks associated with ADT are generally within the same range as those associated with many other commonly prescribed psychotropic interventions.
雄激素剥夺疗法（ADT）可显著降低睾酮水平。这进而会降低性欲，有助于更好地自我控制，并降低性紊乱罪犯的累犯率。潜在的副作用可能包括：骨密度降低；出现涉及体重增加的代谢综合征，并伴有葡萄糖和脂质代谢变化；以及罕见的抑郁症。在存在旨在预防或尽量减少副作用，特别是骨质疏松症发生的适当治疗方案的情况下，ADT相关风险通常与许多其他常用精神药物干预措施的风险范围相同。
