Lefaucheur J-P, Neves D O, Vial C
Service de physiologie-explorations fonctionnelles (neurophysiologie clinique), hôpital Henri-Mondor, 94010 Créteil cedex, France.
Neurochirurgie. 2009 Apr;55(2):136-41. doi: 10.1016/j.neuchi.2009.01.004. Epub 2009 Mar 18.
In various neurosurgical operations, there is a risk of cranial nerve lesion that can be avoided or minimized with intraoperative electrophysiological monitoring. Regarding motor function of the cranial nerves, stimulodetection techniques are used, including electrical stimulation of nerve trunks and electromyographic recording of evoked motor responses. These techniques can be used for monitoring the trigeminal nerve (Vth cranial nerve), facial nerve (VIIth), glossopharyngeal nerve (IXth), pneumogastric nerve (Xth), spinal accessory nerve (XIth), and hypoglossal nerve (XIIth), in particular during surgical removal of tumors of the cerebellopontine angle or skull base. When beginning an operation, electrical stimulation is only used to identify the nerve structures. As removal of the tumor progresses, the goal is to verify that a surgical injury to the nerve is avoided by looking for the absence of any change regarding amplitude, morphology, and latency of motor responses. Intraoperative electromyographic monitoring can also be applied during the surgical treatment of primary hemifacial spasm by microvascular decompression. An effective decompression is usually associated with the disappearance of "lateral spread" motor responses to facial nerve branch stimulation. Therefore, the intraoperative disappearance of the lateral spread responses can be considered a predictive factor of good postoperative clinical outcome, even if this assertion remains a matter of debate.
在各种神经外科手术中,存在颅神经损伤的风险,而术中电生理监测可避免这种风险或使其降至最低。关于颅神经的运动功能,采用刺激检测技术,包括对神经干进行电刺激以及对诱发的运动反应进行肌电图记录。这些技术可用于监测三叉神经(第Ⅴ对颅神经)、面神经(第Ⅶ对)、舌咽神经(第Ⅸ对)、迷走神经(第Ⅹ对)、副神经(第Ⅺ对)和舌下神经(第Ⅻ对),尤其是在手术切除桥小脑角或颅底肿瘤期间。手术开始时,电刺激仅用于识别神经结构。随着肿瘤切除的进展,目标是通过观察运动反应的幅度、形态和潜伏期是否有任何变化来确认避免了对神经的手术损伤。术中肌电图监测也可应用于原发性面肌痉挛微血管减压手术治疗过程中。有效的减压通常与面神经分支刺激的“侧方扩散”运动反应消失相关。因此,即使这一观点仍存在争议,但术中侧方扩散反应的消失可被视为术后良好临床结果的预测因素。