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[一名因创伤性脑损伤导致严重痉挛的儿童鞘内注射巴氯芬的病例报告]

[Case report of intrathecal baclofen administration in a child with severe spasticity attributable to traumatic brain injury].

作者信息

Matsuda Ryosuke, Nishimura Fumihiko, Hirabayashi Hidehiro, Motoyama Yasushi, Mishima Hideaki, Park Young-Su, Nakase Hiroyuki, Sakaki Toshisuke

机构信息

Department of Neurosurgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.

出版信息

Brain Nerve. 2009 Mar;61(3):313-5.

Abstract

We report a pediatric case of intrathecal baclofen therapy for severe spasticity following traumatic brain injury. A 14-year-old boy suffered from traumatic brain injury by traffic accident in 2005. Subsequently, he experienced tetraparesis and severe spasticity with spontaneous spasms. He underwent baclofen screening test, and his spasticity was improved. Thereafter intrathecal baclofen therapy was performed. Following baclofen pump implantation, Ashworth Score decreased from 4.0 points to 3.0 in lower limbs, and from 3.0 to 1.5 in upper limbs. His muscle tone was reduced and occurrence of spontaneous spasms stopped. Intrathecal baclofen therapy was observed to be an effective treatment for severe spasticity in childhood. Since children receiving the therapy demonstrated longer survival period than adults, long-term follow-up of this therapy is warranted.

摘要

我们报告一例小儿创伤性脑损伤后鞘内注射巴氯芬治疗严重痉挛的病例。一名14岁男孩于2005年因交通事故导致创伤性脑损伤。随后,他出现四肢轻瘫和严重痉挛,并伴有自发痉挛。他接受了巴氯芬筛查试验,痉挛症状得到改善。此后进行了鞘内注射巴氯芬治疗。植入巴氯芬泵后,下肢Ashworth评分从4.0分降至3.0分,上肢从3.0分降至1.5分。他的肌张力降低,自发痉挛停止。鞘内注射巴氯芬治疗被认为是治疗儿童严重痉挛的有效方法。由于接受该治疗的儿童生存期比成人更长,因此有必要对该治疗进行长期随访。

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