Animut Abebe, Mekonnen Yalemtsehay, Shimelis Damte, Ephraim Eden
Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Jpn J Infect Dis. 2009 Mar;62(2):107-10.
Fever of different etiology is common in tropical and subtropical countries of the world. Etiological agents of febrile illnesses were assessed in 653 acute febrile patients aged 3 to 17 years who attended the outpatient departments of Dembecha Health Center, Jiga Health Center, Quarit Health Center, and Finoteselam Hospital in western Gojjam zone, northwestern Ethiopia. Malaria was the most prevalent illness, infecting 62% of all cases. Its prevalence varied significantly from 52% (Dembecha) to 72.7% (Quarit) (chi(2)=15.02, P=0.000). Plasmodium falciparum was the first cause of malaria (47.3%) followed by P. vivax (23%). Mixed infection of both P. falciparum and P. vivax was found in 7.2% of the cases. The other febrile infections were pneumonia (7%), typhoid (5.8%), typhus (5.1%), and brucellosis (2.6%). The availability of diagnostic facilities and the awareness of the community regarding the prevalence of non-malaria febrile illnesses are very low, and these illnesses are diagnosed clinically. As these illnesses are nonspecific, especially during the early stages of onset, misdiagnosis and mistreatment can occur. Therefore, it is recommended that the necessary diagnostic materials and awareness should be in place for prompt treatment of febrile cases in these districts.
不同病因引起的发热在世界热带和亚热带国家很常见。对埃塞俄比亚西北部戈贾姆地区西部德姆贝查健康中心、吉加健康中心、夸里特健康中心和菲诺特塞拉姆医院门诊就诊的653名3至17岁急性发热患者的发热病因进行了评估。疟疾是最常见的疾病,感染了所有病例的62%。其患病率从52%(德姆贝查)到72.7%(夸里特)有显著差异(χ²=15.02,P=0.000)。恶性疟原虫是疟疾的首要病因(47.3%),其次是间日疟原虫(23%)。7.2%的病例中发现了恶性疟原虫和间日疟原虫的混合感染。其他发热性感染包括肺炎(7%)、伤寒(5.8%)、斑疹伤寒(5.1%)和布鲁氏菌病(2.6%)。诊断设施的可用性以及社区对非疟疾发热性疾病患病率的认识非常低,这些疾病是通过临床诊断的。由于这些疾病不具有特异性,尤其是在发病早期,可能会发生误诊和误治。因此,建议在这些地区配备必要的诊断材料并提高认识,以便及时治疗发热病例。