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欧洲心脏手术风险评估系统(EuroSCORE)对预测心脏手术后重症监护病房延长住院时间有用吗?

Is EuroSCORE useful in the prediction of extended intensive care unit stay after cardiac surgery?

作者信息

Messaoudi Nouredin, De Cocker Jeroen, Stockman Bernard A, Bossaert Leo L, Rodrigus Inez E R

机构信息

Department of Cardiac Surgery, Antwerp University Hospital, Edegem, Belgium.

出版信息

Eur J Cardiothorac Surg. 2009 Jul;36(1):35-9. doi: 10.1016/j.ejcts.2009.02.007.

Abstract

OBJECTIVE

Risk stratification allows preoperative assessment of cardiac surgical risk faced by individual patients and permits retrospective analysis of postoperative complications in the intensive care unit (ICU). The aim of this single-center study was to investigate the prediction of extended ICU stay after cardiac surgery using both the additive and logistic model of the European System for Cardiac Operative Risk Evaluation (EuroSCORE).

METHODS

A retrospective observational study was conducted. We collected clinical data of 1562 consecutive patients undergoing cardiac surgery over a 2-year period at the Antwerp University Hospital, Belgium. EuroSCORE values of all patients were obtained. The outcome measure was the duration of ICU stay in days. The predictive performance of EuroSCORE was analyzed by the discriminatory power of a receiver operating characteristic (ROC) curve. Each EuroSCORE value was used as a theoretical cut-off point to predict duration of ICU stay. Three subsequent ICU stays were defined as prolonged: more than 2, 5 and 7 days. ROC curves were constructed for both the additive and logistic model.

RESULTS

Patients had a median ICU stay of 2 days and a mean ICU stay of 5.5 days. Median additive EuroSCORE was 5 (range, 0-22) and logistic EuroSCORE was 3.94% (range, 0.00-87.00). In the additive EuroSCORE model, a predictive value of 0.76 for an ICU stay of >7 days, 0.72 for >5 days and 0.67 for >2 days was found. The logistic EuroSCORE model yielded an area under the ROC curve of 0.77, 0.75 and 0.68 for each ICU length of stay, respectively.

CONCLUSIONS

In our patient database, prolonged length of stay in the ICU correlated positively with EuroSCORE. The logistic model was more discriminatory than the additive in tracing extended ICU stay. The overall predictive performance of EuroSCORE is acceptable and most likely based on the presence of variables that are risk factors for both mortality and extended ICU stay. Hence, EuroSCORE is a useful predicting tool and provides both surgeons and intensivists with a good estimate of patient risk in terms of ICU stay.

摘要

目的

风险分层有助于对个体患者面临的心脏手术风险进行术前评估,并能对重症监护病房(ICU)的术后并发症进行回顾性分析。本单中心研究的目的是使用欧洲心脏手术风险评估系统(EuroSCORE)的相加模型和逻辑模型来研究心脏手术后延长ICU住院时间的预测情况。

方法

进行一项回顾性观察研究。我们收集了比利时安特卫普大学医院2年内连续1562例接受心脏手术患者的临床数据。获取了所有患者的EuroSCORE值。观察指标为ICU住院天数。通过受试者操作特征(ROC)曲线的辨别力分析EuroSCORE的预测性能。每个EuroSCORE值用作预测ICU住院时间的理论切点。随后将三种ICU住院情况定义为延长:超过2天、5天和7天。为相加模型和逻辑模型构建ROC曲线。

结果

患者的ICU住院中位时间为2天,平均住院时间为5.5天。相加EuroSCORE的中位数为5(范围0 - 22),逻辑EuroSCORE为3.94%(范围0.00 - 87.00)。在相加EuroSCORE模型中,对于ICU住院时间>7天的预测值为0.76,>5天为0.72,>2天为0.67。逻辑EuroSCORE模型对于每种ICU住院时长的ROC曲线下面积分别为0.77、0.75和0.68。

结论

在我们的患者数据库中,ICU住院时间延长与EuroSCORE呈正相关。在追踪延长的ICU住院时间方面,逻辑模型比相加模型更具辨别力。EuroSCORE的总体预测性能是可接受的,很可能是基于存在既是死亡率又是延长ICU住院时间风险因素的变量。因此,EuroSCORE是一种有用的预测工具,为外科医生和重症监护医生提供了关于患者ICU住院风险的良好估计。

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