脑病变的立体定向活检
Stereotactic biopsies of brain lesions.
作者信息
Teixeira Manoel Jacobsen, Fonoff Erich Talamoni, Mandel Mauricio, Alves Hélvio Leite, Rosemberg Sérgio
机构信息
Departamento de Neurologia, Faculdade de Medicina, Universidade Estadual de São Paulo, São Paulo, SP, Brazil.
出版信息
Arq Neuropsiquiatr. 2009 Mar;67(1):74-7. doi: 10.1590/s0004-282x2009000100018.
OBJECTIVE
In the majority of cases, the correct treatment of brain lesions is possible only when the histopathological diagnosis is made. Several deep-seated lesions near eloquent areas are not safely approached by the classical neurosurgical procedures. These patients can get benefit by a minimally invasive procedure.
METHOD
We present a series of 176 consecutive patients submitted to stereotactic biopsies due to a great variety of brain lesions.
RESULTS
Histological diagnosis found in this series: glioma in 40.1% of the patients, other neoplasms in 12.2% and infectious or inflammatory diseases in 29.1 %. The result was inconclusive in 5.2% of the procedures. One patient died (0.6%) and two (1.2%) presented operative complications. The criteria, advantages and risks of the stereotactic biopsies are discussed.
CONCLUSION
The efficacy of the method is adequate and morbid-mortality rates were low.
目的
在大多数情况下，只有进行组织病理学诊断后才能对脑病变进行正确治疗。经典神经外科手术无法安全地处理一些位于功能区附近的深部病变。这些患者可通过微创手术获益。
方法
我们报告了一系列因各种脑病变而接受立体定向活检的176例连续患者。
结果
本系列病例的组织学诊断结果为：40.1%的患者为胶质瘤，12.2%为其他肿瘤，29.1%为感染性或炎性疾病。5.2%的手术结果不明确。1例患者死亡（0.6%），2例（1.2%）出现手术并发症。讨论了立体定向活检的标准、优点和风险。
结论
该方法疗效良好，病死率较低。
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