Pediatrics. 2009 May;123(5):1412-20. doi: 10.1542/peds.2009-0466. Epub 2009 Mar 30.
This statement updates and replaces the 2007 American Academy of Pediatrics statement for prevention of rotavirus gastroenteritis. In February 2006, a live oral human-bovine reassortant rotavirus vaccine (RV5 [RotaTeq]) was licensed as a 3-dose series for use in infants in the United States. The American Academy of Pediatrics recommended routine use of RV5 in infants in the United States. In April 2008, a live, oral, human attenuated rotavirus vaccine (RV1 [Rotarix]) was licensed as a 2-dose series for use in infants in the United States. The American Academy of Pediatrics recommends routine immunization of infants in the United States with rotavirus vaccine. The American Academy of Pediatrics does not express a preference for either RV5 or RV1. RV5 is to be administered orally in a 3-dose series with doses administered at 2, 4, and 6 months of age; RV1 is to be administered orally in a 2-dose series with doses administered at 2 and 4 months of age. The first dose of rotavirus vaccine should be administered from 6 weeks through 14 weeks, 6 days of age. The minimum interval between doses of rotavirus vaccine is 4 weeks. All doses should be administered by 8 months, 0 days of age. Recommendations in this statement also address the maximum ages for doses, contraindications, precautions, and special situations for administration of rotavirus vaccine.
本声明更新并取代了2007年美国儿科学会关于预防轮状病毒胃肠炎的声明。2006年2月，一种口服人-牛重组轮状病毒活疫苗（RV5 [Rotateq]）获得许可，作为三剂系列疫苗用于美国婴儿。美国儿科学会建议在美国婴儿中常规使用RV5。2008年4月，一种口服人减毒轮状病毒活疫苗（RV1 [Rotarix]）获得许可，作为两剂系列疫苗用于美国婴儿。美国儿科学会建议在美国对婴儿进行轮状病毒疫苗常规免疫。美国儿科学会对RV5和RV1均无偏好。RV5以三剂系列口服给药，分别在2、4和6月龄时接种；RV1以两剂系列口服给药，分别在2和4月龄时接种。轮状病毒疫苗的第一剂应在6周龄至14周龄6天之间接种。轮状病毒疫苗各剂之间的最短间隔为4周。所有剂次均应在8月龄0天时接种。本声明中的建议还涉及轮状病毒疫苗接种的最大年龄、禁忌证、注意事项及特殊接种情况。
