鉴定Ku抗原的Ku80亚基为一种与无嘌呤/无嘧啶位点反应的蛋白质。 - Suppr

Identification of Ku80 subunit of Ku antigen as a protein reactive to apurinic/apyrimidinic sites.

作者信息

Ilina E S, Lavrik O I, Khodyreva S N

机构信息

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk.

出版信息

Dokl Biochem Biophys. 2009 Jan-Feb;424:31-4. doi: 10.1134/s1607672909010098.

DOI:10.1134/s1607672909010098

PMID:19341103

Abstract

摘要

相似文献

Identification of Ku80 subunit of Ku antigen as a protein reactive to apurinic/apyrimidinic sites.

Dokl Biochem Biophys. 2009 Jan-Feb;424:31-4. doi: 10.1134/s1607672909010098.

Ku antigen interacts with abasic sites.

Biochim Biophys Acta. 2008 Nov;1784(11):1777-85. doi: 10.1016/j.bbapap.2008.08.001. Epub 2008 Aug 13.

Ku antigen displays the AP lyase activity on a certain type of duplex DNA.

Biochim Biophys Acta. 2016 Sep;1864(9):1244-1252. doi: 10.1016/j.bbapap.2016.04.011. Epub 2016 Apr 26.

Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.

Nature. 2010 Apr 22;464(7292):1214-7. doi: 10.1038/nature08926. Epub 2010 Apr 11.

Requirements for 5'dRP/AP lyase activity in Ku.

Nucleic Acids Res. 2014;42(17):11136-43. doi: 10.1093/nar/gku796. Epub 2014 Sep 8.

Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF).

J Biol Chem. 2013 Jul 5;288(27):19604-13. doi: 10.1074/jbc.M112.440388. Epub 2013 May 20.

Poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites.

Dokl Biochem Biophys. 2010 Mar-Apr;431:69-72. doi: 10.1134/s1607672910020043.

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.

J Biol Chem. 2016 Dec 30;291(53):26987-27006. doi: 10.1074/jbc.M116.751867. Epub 2016 Nov 14.

Is DNA repair compromised in Alzheimer's disease?

Neurobiol Aging. 2003 Nov;24(7):953-68. doi: 10.1016/s0197-4580(02)00229-4.

The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium.

J Biol Chem. 1996 Apr 12;271(15):8593-8. doi: 10.1074/jbc.271.15.8593.

引用本文的文献

Poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites.

Dokl Biochem Biophys. 2010 Mar-Apr;431:69-72. doi: 10.1134/s1607672910020043.

本文引用的文献

The biology of Ku and its potential oncogenic role in cancer.

Biochim Biophys Acta. 2006 Apr;1765(2):223-34. doi: 10.1016/j.bbcan.2006.01.001. Epub 2006 Jan 25.

Proteomic approach to identification of proteins reactive for abasic sites in DNA.

Mol Cell Proteomics. 2006 May;5(5):858-67. doi: 10.1074/mcp.M500224-MCP200. Epub 2006 Feb 11.

Photoaffinity labeling technique for studying DNA replication and DNA repair.

Curr Med Chem. 2005;12(6):641-55. doi: 10.2174/0929867053202179.

A new highly efficient photoreactive analogue of dCTP. Synthesis, characterization, and application in photoaffinity modification of DNA binding proteins.

Bioconjug Chem. 2005 Jan-Feb;16(1):215-22. doi: 10.1021/bc0497867.

A means to a DNA end: the many roles of Ku.

Nat Rev Mol Cell Biol. 2004 May;5(5):367-78. doi: 10.1038/nrm1367.

Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae.

DNA Repair (Amst). 2004 Jan 5;3(1):1-12. doi: 10.1016/j.dnarep.2003.10.002.

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

Mutat Res. 2001 May 10;485(4):283-307. doi: 10.1016/s0921-8777(01)00063-5.

Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair.

J Biol Chem. 2001 Jul 6;276(27):25541-8. doi: 10.1074/jbc.M102125200. Epub 2001 May 4.

A possible role of Ku in mediating sequential repair of closely opposed lesions.

J Biol Chem. 2001 Apr 20;276(16):12827-31. doi: 10.1074/jbc.M010906200. Epub 2001 Jan 25.

AP lyases and dRPases: commonality of mechanism.

Mutat Res. 2000 Feb 16;459(1):43-53. doi: 10.1016/s0921-8777(99)00054-3.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

Identification of Ku80 subunit of Ku antigen as a protein reactive to apurinic/apyrimidinic sites.

Dokl Biochem Biophys. 2009 Jan-Feb;424:31-4. doi: 10.1134/s1607672909010098.

Ku antigen interacts with abasic sites.

Biochim Biophys Acta. 2008 Nov;1784(11):1777-85. doi: 10.1016/j.bbapap.2008.08.001. Epub 2008 Aug 13.

Ku antigen displays the AP lyase activity on a certain type of duplex DNA.

Biochim Biophys Acta. 2016 Sep;1864(9):1244-1252. doi: 10.1016/j.bbapap.2016.04.011. Epub 2016 Apr 26.

Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.

Nature. 2010 Apr 22;464(7292):1214-7. doi: 10.1038/nature08926. Epub 2010 Apr 11.

Requirements for 5'dRP/AP lyase activity in Ku.

Nucleic Acids Res. 2014;42(17):11136-43. doi: 10.1093/nar/gku796. Epub 2014 Sep 8.

Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF).

J Biol Chem. 2013 Jul 5;288(27):19604-13. doi: 10.1074/jbc.M112.440388. Epub 2013 May 20.

Poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites.

Dokl Biochem Biophys. 2010 Mar-Apr;431:69-72. doi: 10.1134/s1607672910020043.

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.

J Biol Chem. 2016 Dec 30;291(53):26987-27006. doi: 10.1074/jbc.M116.751867. Epub 2016 Nov 14.

Is DNA repair compromised in Alzheimer's disease?

Neurobiol Aging. 2003 Nov;24(7):953-68. doi: 10.1016/s0197-4580(02)00229-4.

The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium.

J Biol Chem. 1996 Apr 12;271(15):8593-8. doi: 10.1074/jbc.271.15.8593.

引用本文的文献

Poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites.

Dokl Biochem Biophys. 2010 Mar-Apr;431:69-72. doi: 10.1134/s1607672910020043.

本文引用的文献

The biology of Ku and its potential oncogenic role in cancer.

Biochim Biophys Acta. 2006 Apr;1765(2):223-34. doi: 10.1016/j.bbcan.2006.01.001. Epub 2006 Jan 25.

Proteomic approach to identification of proteins reactive for abasic sites in DNA.

Mol Cell Proteomics. 2006 May;5(5):858-67. doi: 10.1074/mcp.M500224-MCP200. Epub 2006 Feb 11.

Photoaffinity labeling technique for studying DNA replication and DNA repair.

Curr Med Chem. 2005;12(6):641-55. doi: 10.2174/0929867053202179.

A new highly efficient photoreactive analogue of dCTP. Synthesis, characterization, and application in photoaffinity modification of DNA binding proteins.

Bioconjug Chem. 2005 Jan-Feb;16(1):215-22. doi: 10.1021/bc0497867.

A means to a DNA end: the many roles of Ku.

Nat Rev Mol Cell Biol. 2004 May;5(5):367-78. doi: 10.1038/nrm1367.

Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae.

DNA Repair (Amst). 2004 Jan 5;3(1):1-12. doi: 10.1016/j.dnarep.2003.10.002.

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

Mutat Res. 2001 May 10;485(4):283-307. doi: 10.1016/s0921-8777(01)00063-5.

Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair.

J Biol Chem. 2001 Jul 6;276(27):25541-8. doi: 10.1074/jbc.M102125200. Epub 2001 May 4.

A possible role of Ku in mediating sequential repair of closely opposed lesions.

J Biol Chem. 2001 Apr 20;276(16):12827-31. doi: 10.1074/jbc.M010906200. Epub 2001 Jan 25.

AP lyases and dRPases: commonality of mechanism.

Mutat Res. 2000 Feb 16;459(1):43-53. doi: 10.1016/s0921-8777(99)00054-3.

Identification of Ku80 subunit of Ku antigen as a protein reactive to apurinic/apyrimidinic sites.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献