Wang Qing, Lu Xiao-Jie, Li Bing, Ji Wei-Yang, Chen Kai-Lai
Department of Neurosurgery, Wuxi Second Hospital Affiliated Nanjing Medical University, 68 Zhong Shan Road, Wuxi 214002, Jiangsu Province, China.
J Clin Neurosci. 2009 Jul;16(7):889-93. doi: 10.1016/j.jocn.2008.10.003. Epub 2009 Apr 2.
In this present study, we reviewed our management of seven patients by an extended endoscopic endonasal transsphenoidal approach to resect tuberculum sellae meningiomas. All surgery was performed using pure endoscopy and a neuronavigation system. In six patients, total resection of the tumor was accomplished; one patient had subtotal tumor removal. Post-operatively, visual function was improved in six patients, and was unchanged in one patient. There was asymptomatic tumor recurrence on MRI during the follow-up period in the patient in whom a subtotal resection had been performed. This preliminary report suggests that an extended endoscopic endonasal transsphenoidal approach is an effective, minimally invasive approach for small and medium-sized tuberculum sellae meningiomas located in the midline. However, this approach should be limited to an experienced and coordinated endoneurosurgical team.
在本研究中,我们回顾了通过扩大经鼻内镜经蝶窦入路切除鞍结节脑膜瘤的7例患者的治疗情况。所有手术均采用单纯内镜和神经导航系统进行。6例患者实现了肿瘤全切;1例患者肿瘤次全切除。术后,6例患者的视力功能得到改善,1例患者视力无变化。接受次全切除的患者在随访期间MRI检查发现有无症状肿瘤复发。这份初步报告表明,扩大经鼻内镜经蝶窦入路对于位于中线的中小型鞍结节脑膜瘤是一种有效、微创的方法。然而,这种方法应限于经验丰富且协作良好的神经内镜手术团队。