棕色脂肪代谢的新变化。
A new twist on brown fat metabolism.
作者信息
Wallberg-Henriksson Harriet, Zierath Juleen R
机构信息
Department of Molecular Medicine and Surgery, Section of Integrative Physiology, Karolinska Institutet, S-171 77 Stockholm, Sweden.
出版信息
Cell. 2009 Apr 3;137(1):22-4. doi: 10.1016/j.cell.2009.03.029.
PMID:19345181
Abstract
The transcriptional coactivator PGC-1alpha promotes mitochondrial biogenesis and thermogenic programs in brown adipose tissue. Pan et al. (2009) identify the transcription factor twist-1 as a negative feedback regulator of PGC-1alpha.
摘要
转录共激活因子PGC-1α可促进棕色脂肪组织中的线粒体生物合成和产热程序。Pan等人（2009年）确定转录因子twist-1为PGC-1α的负反馈调节因子。
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