Oliveira Flávia Schlittler, Pinfildi Carlos Eduardo, Parizoto Nivaldo Antônio, Liebano Richard Eloin, Bossini Paulo Sergio, Garcia Elvio Bueno, Ferreira Lydia Masako
Department of Plastic Surgery, São Paulo Federal University-UNIFESP, São Paulo, SP 04024-900, Brazil.
Lasers Surg Med. 2009 Apr;41(4):271-6. doi: 10.1002/lsm.20760.
Calcaneous tendon is one of the most damaged tendons, and its healing may last from weeks to months to be completed. In the search after speeding tendon repair, low intensity laser therapy has shown favorable effect. To assess the effect of low intensity laser therapy on the process of tissue repair in calcaneous tendon after undergoing a partial lesion.
STUDY DESIGN/MATERIALS AND METHODS: Experimentally controlled randomized single blind study. Sixty male rats were used randomly and were assigned to five groups containing 12 animals each one; 42 out of 60 underwent lesion caused by dropping a 186 g weight over their Achilles tendon from a 20 cm height. In Group 1 (standard control), animals did not suffer the lesion nor underwent laser therapy; in Group 2 (control), animals suffered the lesion but did not undergo laser therapy; in Groups 3, 4, and 5, animals suffered lesion and underwent laser therapy for 3, 5, and 7 days, respectively. Animals which suffered lesion were sacrificed on the 8th day after the lesion and assessed by polarization microscopy to analyze the degree of collagen fibers organization.
Both experimental and standard control Groups presented significant values when compared with the control Groups, and there was no significant difference when Groups 1 and 4 were compared; the same occurred between Groups 3 and 5.
Low intensity laser therapy was effective in the improvement of collagen fibers organization of the calcaneous tendon after undergoing a partial lesion.
跟腱是最易受损的肌腱之一,其愈合可能需要数周甚至数月才能完成。在寻求加速肌腱修复的方法中,低强度激光疗法已显示出良好效果。为评估低强度激光疗法对部分损伤后跟腱组织修复过程的影响。
研究设计/材料与方法:实验对照随机单盲研究。随机选用60只雄性大鼠,分为五组,每组12只;60只中有42只通过从20厘米高处向其跟腱掉落186克重物造成损伤。第1组(标准对照组),动物既未遭受损伤也未接受激光治疗;第2组(对照组),动物遭受损伤但未接受激光治疗;第3、4、5组,动物遭受损伤并分别接受3、5、7天的激光治疗。遭受损伤的动物在损伤后第8天处死,通过偏振显微镜评估以分析胶原纤维的排列程度。
与对照组相比,实验组和标准对照组均呈现出显著数值,第1组和第4组比较无显著差异;第3组和第5组之间情况相同。
低强度激光疗法对改善部分损伤后跟腱的胶原纤维排列有效。