Tigges Frauke, Bauer Andrea, Hochauf Kristina, Meurer Michael
Department of Dermatology, Medical University of Dresden, Germany.
Acta Dermatovenerol Alp Pannonica Adriat. 2009 Mar;18(1):31-4.
A case of a sporotrichoid cutaneous infection caused by Mycobacterium marinum is reported. A 53- year-old male patient presented with red, partly purulent nodular lesions on the back of his left hand, forearm, and upper medial arm that had developed consecutively during the past 4 weeks. A mycobacterial infection with M. marinum was confirmed by molecular methods in a lesional skin biopsy. The patient was treated systemically with rifampicin (750 mg/day) and clarithromycine (1,000 mg/day), and topically with sulmycin (gentamicin sulfate). After 12 weeks of treatment the nodules regressed, leaving behind erythematous patches. M. marinum is a waterborne mycobacterium that commonly infects fish and amphibians worldwide. Transmissions to humans occur occasionally, in most cases as a granulomatous infection localized to the skin, typically following minor trauma to the hands. For this reason, infections are especially common among aquarium keepers.
报告了一例由海分枝杆菌引起的孢子丝菌样皮肤感染病例。一名53岁男性患者,左手背、前臂和上臂内侧出现红色、部分脓性结节性病变,这些病变在过去4周内陆续出现。通过对病变皮肤活检进行分子方法检测,确诊为海分枝杆菌感染。患者接受了利福平(750毫克/天)和克拉霉素(1000毫克/天)的全身治疗,以及磺胺米隆(硫酸庆大霉素)的局部治疗。治疗12周后,结节消退,留下红斑。海分枝杆菌是一种水生分枝杆菌,在全球范围内通常感染鱼类和两栖动物。偶尔会传播给人类,大多数情况下表现为局限于皮肤的肉芽肿性感染,通常在手部受到轻微创伤后发生。因此,感染在水族馆饲养员中尤为常见。