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2007年晚期结直肠癌治疗的成果。

Accomplishments in 2007 in the treatment of advanced colorectal cancer.

作者信息

Goldberg Richard M, Carrato Alfredo

机构信息

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.

出版信息

Gastrointest Cancer Res. 2008 May;2(3 Suppl):S19-24.

Abstract

Overview of the Disease IncidencePrognosis Prognostic or Predictive FactorsCurrent General Therapy Standards and Regional Variations STANDARDS IN THE US AND EUROPE: Combination Therapy Plus a Biologic FOCUS and CAIRO 1: Serial Single Agents vs. Combination TherapyStop-and-Go StrategyLimited Availability of Biologics in Some RegionsAccomplishments During the Year TherapyWhat Needs To Be Done Controversies and Disagreements BOND-2 and PACCE: Chemotherapy + Bevacizumab + Cetuximab or PanitumumabSpecial Populations (Elderly and Poor Performance Status)Future Directions Comments on ResearchObstacles to Progress.

摘要

疾病发病率概述、预后、预后或预测因素、当前一般治疗标准及地区差异、美国和欧洲的标准:联合治疗加生物制剂、FOCUS和CAIRO 1:序贯单药治疗与联合治疗、停停走走策略、某些地区生物制剂供应有限、年度治疗成果、有待完成的事项、争议与分歧、BOND-2和PACCE:化疗+贝伐单抗+西妥昔单抗或帕尼单抗、特殊人群(老年人和体能状态差者)、未来方向、对研究的评论、进展障碍

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