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行业支持的普遍性及其与研究诚信的关系。

Prevalence of industry support and its relationship to research integrity.

作者信息

Tereskerz Patricia M, Hamric Ann B, Guterbock Thomas M, Moreno Jonathan D

机构信息

Program in Ethics and Policy in Healthcare, Center for Biomedical Ethics and Humanities, University of Virginia School of Medicine, Charlottesville, Virginia, USA.

出版信息

Account Res. 2009 Apr-Jun;16(2):78-105. doi: 10.1080/08989620902854945.

Abstract

Most U.S. clinical trials are funded by industry. Opportunities exist for sponsors to influence research in ways that jeopardize research objectivity. The purpose of this study was to survey U.S. medical school faculty to assess financial arrangements between investigators and industry to learn about investigators' first hand knowledge of the effects of industry sponsorship on research. Here we show first-hand knowledge that compromises occurred in: research participants' well-being (9%), research initiatives (35%), publication of results (28%), interpretation of research data (25%), and scientific advancement (20%) because of industry support. Financial relationships with industry were prevalent and considered important to conducting respondents' research.

摘要

大多数美国临床试验由企业资助。赞助商存在以危及研究客观性的方式影响研究的可能性。本研究的目的是对美国医学院教员进行调查,以评估研究者与企业之间的财务安排,从而了解研究者对企业赞助对研究影响的第一手认知。在此我们展示了第一手认知,即由于企业支持,在以下方面出现了损害:研究参与者的福祉(9%)、研究计划(35%)、研究结果的发表(28%)、研究数据的解读(25%)以及科学进步(20%)。与企业的财务关系普遍存在,且被认为对开展受访者的研究很重要。

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