Younis Tallal, Milch Robert, Abul-Khoudoud Nawal, Lawrence David, Mirand Amy, Levine Ellis
Queen Elizabeth II Health Sciences Centre, Nova Scotia, Canada.
Am J Hosp Palliat Care. 2009 Aug-Sep;26(4):281-7. doi: 10.1177/1049909109333928. Epub 2009 Apr 8.
This retrospective study examined 180 hospice patients referred from a comprehensive cancer center over 6 months in 2002 to (1) identify the variables associated with shorter length of survival (LOS) in hospice and (2) examine the LOS in hospice for those who previously participated in clinical trials and/or phase I studies. The median LOS in hospice for this cohort was 35 days. In multivariate analysis, low Palliative Performance Score (PPS) at hospice enrollment and male gender were associated with shorter LOS in hospice: males with low PPS had the shortest LOS while females with high PPS had the longest LOS. No correlation was found between the LOS in hospice and prior participation in clinical trials and/or phase I studies.
这项回顾性研究调查了2002年6个月内从一家综合癌症中心转诊的180名临终关怀患者,以(1)确定与临终关怀中较短生存期相关的变量,以及(2)检查那些先前参与过临床试验和/或I期研究的患者在临终关怀中的生存期。该队列临终关怀的中位生存期为35天。在多变量分析中,临终关怀入院时的低姑息治疗表现评分(PPS)和男性性别与临终关怀中较短的生存期相关:低PPS的男性生存期最短,而高PPS的女性生存期最长。未发现临终关怀中的生存期与先前参与临床试验和/或I期研究之间存在相关性。