基于血红蛋白的氧载体：益处是否值得冒风险？

Haemoglobin-based oxygen carriers: is the benefit worth the risk?

作者信息

Mackenzie Colin F

机构信息

Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

出版信息

Br J Hosp Med (Lond). 2009 Jan;70(1):26-30. doi: 10.12968/hmed.2009.70.1.37691.

DOI:10.12968/hmed.2009.70.1.37691

PMID:19357574

Abstract

When blood is indicated but not available, haemoglobin-based oxygen carriers can sustain oxygen carriage in acute anaemia, expand circulating volume and improve rheology to ischaemic tissues. When blood is limited, not available or not an option, the risks associated with these carriers must be weighed against the risk of death.

摘要

当有输血指征但无血液可用时，基于血红蛋白的氧载体可在急性贫血中维持氧运输，扩充循环血容量，并改善缺血组织的血液流变学。当血液有限、无法获取或不可行时，必须权衡这些载体相关的风险与死亡风险。