Manolakaki Dimitra, Velmahos George C, Spaniolas Konstantinos, de Moya Marc, Alam Hasan B
Division of Trauma Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
J Trauma. 2009 Apr;66(4):1008-12; discussion 1012-4. doi: 10.1097/TA.0b013e31819adba2.
Computed tomography (CT) is routinely performed in traumatic brain injury (TBI). Magnetic resonance imaging (MRI) is considered more sensitive than CT for subtle abnormalities. Because CT does not always explain the posttraumatic neurologic examination, MRI is being performed with increasing frequency. Although MRI at a later stage may be of significant prognostic value, the role of early MRI is questionable. Our objective was to evaluate the role of early MRI in the initial management of patients with TBI.
This is a 3-year prospective study (January 2005-December 2007) of adult patients with TBI who, in addition to CT, had MRI of the head within 48 hours of admission to the hospital. The findings from the two imaging studies were compared. The outcome was any change in management based on MRI findings.
We identified 123 trauma patients who had MRI within 18 hours +/- 14.5 hours of CT (median: 12 hours). In 82 (67%) patients, the findings of CT and MRI were identical. In the remaining 41 patients there were discrepancies between CT and MRI: 35 patients had slight differences in the location or size of the lesions found and six had minor brain lesion detected by MRI and not CT. Compared with patients who had identical CT and MRI, those who showed differences in the two tests had higher severity of head injury, lower initial blood pressure, and a higher rate of intubation. Based on CT findings, 78 (63%) patients received TBI-related interventions: 8 craniotomies, 12 intracranial pressure monitoring catheters, 14 mannitol infusions, and 72 antiepileptic medications. There was no change in treatment because of MRI.
Early MRI may be superior to CT in describing subtle TBI findings, but this information does not affect management. Head CT is the only imaging test necessary in the first 48 hours after TBI.
计算机断层扫描(CT)是创伤性脑损伤(TBI)的常规检查手段。磁共振成像(MRI)对于细微异常的检测被认为比CT更为敏感。由于CT并不总能解释创伤后的神经学检查结果,因此MRI的检查频率日益增加。尽管后期的MRI可能具有重要的预后价值,但早期MRI的作用仍存在疑问。我们的目的是评估早期MRI在TBI患者初始治疗中的作用。
这是一项为期3年的前瞻性研究(2005年1月至2007年12月),研究对象为成年TBI患者,这些患者除了接受CT检查外,还在入院后48小时内接受了头部MRI检查。对两项影像学检查的结果进行了比较。结果是基于MRI结果的任何治疗调整。
我们确定了123例创伤患者,他们在CT检查后18小时±14.5小时(中位数:12小时)内接受了MRI检查。在82例(67%)患者中,CT和MRI的结果一致。在其余41例患者中,CT和MRI结果存在差异:35例患者发现的病变位置或大小略有不同,6例患者MRI检测到轻微脑损伤而CT未检测到。与CT和MRI结果一致的患者相比,两项检查结果存在差异的患者头部损伤更严重,初始血压更低,插管率更高。基于CT结果,78例(63%)患者接受了与TBI相关的干预措施:8例开颅手术,12例颅内压监测导管置入,14例甘露醇输注,72例抗癫痫药物治疗。未因MRI结果而改变治疗方案。
早期MRI在描述细微的TBI表现方面可能优于CT,但这些信息并不影响治疗。头部CT是TBI后48小时内唯一必要的影像学检查。