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[新生儿沙眼衣原体感染——当前实验室诊断概述]

[Chlamydia trachomatis infections in neonates--overview of current laboratory diagnostics].

作者信息

Balla Eszter

机构信息

Országos Epidemiológiai Központ, II. Bakteriológiai Osztály, Budapest.

出版信息

Orv Hetil. 2009 Apr 26;150(17):805-9. doi: 10.1556/OH.2009.28601.

Abstract

Based on recent literature and their own laboratory experiences the author summarizes the clinical manifestations, diagnostic possibilities and the tools of prevention of neonatal Chlamydia trachomatis infection, where a potential or a verified role of this pathogen is present. Definitive diagnosis is complicated by the common phenomenon of asymptomatic, undiagnosed maternal infection, as well as by the need for adequate sample-collection and targetted screening techniques. There are only estimated data regarding the incidence of neonatal Chlamydia trachomatis infection; however we do have the diagnostic tests to identify the affected neonates, who may have generally only a mild-moderate manifestation of infection in case of an early treatment. Focussed screening efforts should be made to reduce the number of infected pregnant women and thereby the vertical rate of transmission.

摘要

基于近期文献及自身实验室经验,作者总结了新生儿沙眼衣原体感染的临床表现、诊断方法及预防措施,其中该病原体存在潜在或已证实的作用。由于无症状、未被诊断的母体感染这一常见现象,以及对充分样本采集和针对性筛查技术的需求,明确诊断变得复杂。关于新生儿沙眼衣原体感染的发病率仅有估计数据;然而,我们确实拥有诊断测试来识别受感染的新生儿,早期治疗的情况下,这些新生儿通常仅有轻度至中度感染表现。应集中开展筛查工作,以减少感染孕妇的数量,从而降低垂直传播率。

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