Department of Obstetrics and Gynecology, Ankara University Medical Faculty, Cebeci, Ankara, Turkey.
Arch Gynecol Obstet. 2010 Jan;281(1):117-8. doi: 10.1007/s00404-009-1075-3. Epub 2009 Apr 11.
Humoral hypercalcemia of malignancy is an important cause of hypercalcemia associated with malignancies and has been rarely reported because of vulvar cancer.
A 65-year-old woman performed modified radical vulvectomy and bilateral lymph node dissection because of vulvar cancer was referred to our clinic with fatigue and somnolence 4 months after her operation. Calcium level was 15.9 mg/dL. There was no bone metastasis, and hypercalcemia was thought as paraneoplastic syndrome because of distant recurrence of the primary vulvar cancer.
Vulvar cancer and hypercalcemia can be seen together very rarely. However, recurrence should be kept in mind in patients with symptoms and signs of hypercalcemia.
恶性肿瘤所致高钙血症是一种与恶性肿瘤相关的高钙血症的重要原因,但由于外阴癌少见,故鲜有报道。
一名 65 岁女性因外阴癌接受改良根治性外阴切除术和双侧淋巴结清扫术,术后 4 个月因乏力和嗜睡就诊于我院。血钙为 15.9mg/dL。无骨转移,由于原发性外阴癌远处复发,高钙血症被认为是副瘤综合征。
外阴癌和高钙血症很少同时出现。然而,对于有高钙血症症状和体征的患者,应考虑复发的可能性。