Fu Weili, Luo Dahui, Ye Jingbing, Chen Ying, Li Qi, Li Jian
Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, PR China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2009 Mar;23(3):278-81.
To evaluate the feasibility and effectiveness of allograft osteochondral transplantation with arthroscopic assistance for osteochondritis dissecans (OCD) associated with large osteochondral defects.
From January 2004 to May 2007, 13 patients with OCD with large osteochondral defects were treated. There were 7 males and 6 females, aged 18-59 years with an average of 35.8 years. The locations were left side in 8 cases and right side in 5 cases. The disease course was 7 days to 20 years with the median duration of 42 months. Four cases had obvious sprained history. The involved locations were lateral portion of the medial femur condyle (MFC) in 5 cases, trochlea area of MFC in 2 cases and lateral femur condyle in 6 cases. The range of motion was (95.0 +/- 13.5) degrees and the Lysholm score was 62.23 +/- 7.79. According to International Cartilage Repair Society classification system and the Guhl classification of OCD under arthroscopy, all the patients were type IV. Defect areas were 3-7 cm2 with an average of 4.32 cm2. The depths of defects were 0.8-2.0 cm with an average of 1.55 cm. Allograft osteochondral transplantation combining with adsorbable screw was applied for the lesions. The patients were closely instructed to do exercise through following up.
The wounds all healed by first intention. Thirteen cases were followed up for 2.2 years (14 months to 4 years) after operation. Three months after operation, 2 cases had pain after continuous exercise for 1 hour, they were directed in the methods of functional exercise and to strengthen their quadriceps femoris. Medicine was given in 2 patients who had sign of friction feeling of joint 6 months after operation. The range of motion at the last follow-up was (137.0 +/- 9.8) degrees, showing statistically significant difference when compared with that before operation (P < 0.05). The X-rays and EMRI examinations at following-up indicated that bone healed well and articular facet was integrity. The Lysholm score was 92.08 +/- 7.64 one year after operation, showing statistically significant difference when compared with that before operation (P < 0.05).
Allograft osteochondral transplantation with arthroscopic assistance is a useful method in treatment of OCD with large osteochondral defects of the knees.
评估关节镜辅助下同种异体骨软骨移植治疗剥脱性骨软骨炎(OCD)合并大的骨软骨缺损的可行性和有效性。
2004年1月至2007年5月,治疗13例OCD合并大的骨软骨缺损患者。其中男性7例,女性6例,年龄18 - 59岁,平均35.8岁。左侧8例,右侧5例。病程7天至20年,中位病程42个月。4例有明显扭伤史。受累部位:内侧股骨髁(MFC)外侧部分5例,MFC滑车区2例,外侧股骨髁6例。活动范围为(95.0±13.5)度,Lysholm评分为62.23±7.79。根据国际软骨修复协会分类系统及关节镜下OCD的Guhl分类,所有患者均为IV型。缺损面积3 - 7 cm²,平均4.32 cm²。缺损深度0.8 - 2.0 cm,平均1.55 cm。采用同种异体骨软骨移植联合可吸收螺钉治疗病变。通过随访密切指导患者进行锻炼。
伤口均一期愈合。13例患者术后随访2.2年(14个月至4年)。术后3个月,2例患者持续锻炼1小时后出现疼痛,对其进行功能锻炼方法指导并加强股四头肌锻炼。2例术后6个月有关节摩擦感体征的患者给予药物治疗。末次随访时活动范围为(137.0±9.8)度,与术前相比差异有统计学意义(P < 0.05)。随访时X线和EMRI检查显示骨愈合良好,关节面完整。术后1年Lysholm评分为92.08±7.64,与术前相比差异有统计学意义(P < 0.05)。
关节镜辅助下同种异体骨软骨移植是治疗膝关节OCD合并大的骨软骨缺损的一种有效方法。