癌症护理中细胞、分子和基因组技术的卫生服务研究议程。
A health services research agenda for cellular, molecular and genomic technologies in cancer care.
作者信息
Wideroff Louise, Phillips Kathryn A, Randhawa Gurvaneet, Ambs Anita, Armstrong Katrina, Bennett Charles L, Brown Martin L, Donaldson Molla S, Follen Michele, Goldie Sue J, Hiatt Robert A, Khoury Muin J, Lewis Graham, McLeod Howard L, Piper Margaret, Powell Isaac, Schrag Deborah, Schulman Kevin A, Scott Joan
机构信息
National Cancer Institute, Bethesda, MD, USA.
出版信息
Public Health Genomics. 2009;12(4):233-44. doi: 10.1159/000203779. Epub 2009 Feb 20.
BACKGROUND
In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care.
METHODS
In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care.
RESULTS
This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations.
CONCLUSIONS
Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings.
背景
近几十年来，已投入大量资源来开发具有临床应用价值的细胞、分子和基因组技术，这些技术贯穿癌症治疗的全过程。
方法
2006年12月，美国国立癌症研究所主办了首次研讨会，专门审视癌症相关细胞、分子和基因组技术的卫生服务研究状况，并确定在扩大其在常规治疗中有效性证据基础方面的挑战和优先事项。
结果
本文总结了研讨会成果，其中包括制定一项全面的研究议程，该议程纳入了健康与安全终点、利用模式、患者和提供者偏好、护理质量与可及性、差异、经济学和决策建模、癌症结局趋势以及目标人群中与健康相关的生活质量。
结论
最终，成功采用有用的技术将取决于理解并影响那些有助于在“现实世界”环境中采用这些技术并使其发挥效用的患者、提供者、医疗保健系统和社会因素。
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