在存在高浓度苯丙胺的情况下，尿液中可检测到低浓度甲基苯丙胺。

Low concentrations of methamphetamine detectable in urine in the presence of high concentrations of amphetamine.

作者信息

Jemionek John F, Addison Joseph, Past Marilyn R

机构信息

Armed Forces Institute of Pathology, Forensic Toxicology Division, Armed Forces Medical Examiner System, 1413 Research Blvd., Bldg. 102, Rockville, Maryland 20850, USA.

出版信息

J Anal Toxicol. 2009 Apr;33(3):170-3. doi: 10.1093/jat/33.3.170.

DOI:10.1093/jat/33.3.170

PMID:19371467

Abstract

Twenty-two urine specimens reported by military drug-testing laboratories for the presence of high concentrations of amphetamine only were subject to further analysis for the presence of methamphetamine. The 22 urine specimens had concentrations of amphetamine in the range of 28,028 to 241,142 ng/mL. The specimens were also assayed for the respective isomeric ratio of d (S) and l (R) amphetamine and methamphetamine. The results suggest that urine specimens containing high concentrations of amphetamine in which the urine concentration ratio of methamphetamine to amphetamine is less than 0.5% with similar isomeric distribution of d-(S) and l-(R) amphetamine and methamphetamine, respectively, may not necessarily indicate polydrug use.

摘要

军事药物检测实验室报告的仅含有高浓度苯丙胺的22份尿液标本，接受了甲基苯丙胺存在情况的进一步分析。这22份尿液标本中苯丙胺浓度在28,028至241,142纳克/毫升范围内。这些标本还检测了d（S）和l（R）苯丙胺及甲基苯丙胺各自的异构体比例。结果表明，尿液中苯丙胺浓度高、甲基苯丙胺与苯丙胺的尿液浓度比小于0.5%且d-（S）和l-（R）苯丙胺及甲基苯丙胺异构体分布相似的尿液标本，不一定表明存在多药滥用情况。