Kim Kyoung-Ah, Kim Se Won, Park Gunmin, Kwak Beom Seok, Choi Jae Sung, Kim Sun Ho, Yeo Jeong Seok, Kim Eo-Jin
Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang-shi, Gyeonggi-do, Korea.
South Med J. 2009 May;102(5):537-41. doi: 10.1097/SMJ.0b013e3181a06613.
A 48-year-old man presented for evaluation of general weakness. Because he had a history of excessive alcohol use, an abdominal computed tomography scan was obtained, which revealed a left adrenal mass. Hormonal evaluation showed elevated levels of urinary catecholamines. Bilateral hilar lymphadenopathy was detected on a chest radiograph. The suspected diagnosis was asymptomatic pheochromocytoma with sarcoidosis. We performed a mediastinoscopic lymph node biopsy, which was followed by endoscopic adrenalectomy. Histologic tissue analysis confirmed an adrenal pheochromocytoma and sarcoid granulomas in the mediastinal lymph nodes. This case highlights the difficulty in determining the appropriate work up of patients presenting with an adrenal incidentaloma and concomitant systemic disease.
一名48岁男性因全身乏力前来评估。由于他有过量饮酒史,遂进行了腹部计算机断层扫描,结果显示左肾上腺有一肿块。激素评估显示尿儿茶酚胺水平升高。胸部X线片发现双侧肺门淋巴结肿大。疑似诊断为无症状嗜铬细胞瘤合并结节病。我们进行了纵隔镜淋巴结活检,随后进行了内镜下肾上腺切除术。组织学分析证实肾上腺嗜铬细胞瘤以及纵隔淋巴结中有结节病肉芽肿。该病例凸显了确定肾上腺偶发瘤合并全身性疾病患者的适当检查方法的困难。