Reid-Nicholson Michelle, Teague Daniel, White Barry, Ramalingam Preetha, Abdelsayed Rafik
Department of Pathology, Medical College of Georgia, Augusta, Georgia 30912, USA.
Diagn Cytopathol. 2009 Aug;37(8):586-91. doi: 10.1002/dc.21083.
We present a case of malignant ameloblastoma presenting in the posterior mandible and cervical lymph nodes of an African American child. This case is somewhat unusual in that the patient was an adolescent and presented with metastatic disease. This partly clinical as well as cytologic diagnosis was facilitated by the presence of typical ameloblastoma cytology in multiple cervical lymph nodes adjacent to the histologically confirmed intraosseous ameloblastoma. Although cytology is helpful in diagnosing ameloblastoma, its features are by no means definitive as there are several cytologic mimics. A high index of suspicion is therefore necessary to confirm or exclude ameloblastoma when evaluating any jaw lesion and/or adjacent enlarged lymph nodes by cytologic examination. Adequate sampling is paramount to accurate diagnosis, and is especially important when attempting to distinguish ameloblastoma from ameloblastic carcinoma.
我们报告一例发生于一名非裔美国儿童下颌骨后部和颈部淋巴结的恶性成釉细胞瘤。该病例有些不同寻常，因为患者是一名青少年且出现了转移性疾病。多个与组织学确诊的骨内成釉细胞瘤相邻的颈部淋巴结中存在典型的成釉细胞瘤细胞学特征，这有助于进行部分临床及细胞学诊断。虽然细胞学检查有助于诊断成釉细胞瘤，但其特征并非绝对明确，因为存在多种细胞学上的相似情况。因此，在通过细胞学检查评估任何颌骨病变和/或相邻肿大淋巴结时，要确认或排除成釉细胞瘤，必须保持高度的怀疑指数。足够的样本采集对于准确诊断至关重要，在试图将成釉细胞瘤与成釉细胞癌区分开来时尤其重要。
