Chen Edwin S, Terry Mark A, Shamie Neda, Hoar Karen L, Phillips Paul M, Friend Daniel J
Spectrum Eye Physicians, San Jose, California 95129, USA.
Am J Ophthalmol. 2009 Jul;148(1):26-31.e2. doi: 10.1016/j.ajo.2009.01.022. Epub 2009 Apr 17.
To compare a 6-month postoperative vision, endothelial cell loss, and immediate postoperative complications in Descemet stripping automated endothelial keratoplasty (DSAEK) cases performed by an experienced corneal surgeon and his inexperienced fellows using an established technique.
Retrospective analysis of prospectively gathered data in 327 consecutive DSAEK cases.
DSAEK cases performed by fellows vs attending surgeons during a concurrent period were compared for 6-month postoperative best spectacle-corrected visual acuity (BSCVA), endothelial cell loss, and immediate postoperative complications. This series represents the initial consecutive cases performed by 3 cornea fellows using a technique identical to that used by the attending.
After DSAEK, average BSCVA improved from 20/80 to 20/37 in the attending cases and 20/74 to 20/36 in the fellow cases. There was no statistical difference in endothelial cell loss between groups (32% vs 35%). The dislocation rate was 2% in the attending group and 1% in the fellow group. There were no primary graft failures or cases of pupillary block in either group.
This study demonstrates no difference in vision or endothelial cell loss after DSAEK when performed by an experienced corneal surgeon or inexperienced fellows. Postoperative complications also were similar. Results and complications of DSAEK performed by supervised novice fellows can equal those of an experienced DSAEK surgeon.
比较由一位经验丰富的角膜外科医生及其经验不足的助手采用既定技术进行的Descemet膜剥离自动内皮角膜移植术(DSAEK)病例术后6个月的视力、内皮细胞丢失情况以及术后即刻并发症。
对327例连续DSAEK病例前瞻性收集的数据进行回顾性分析。
比较同期由助手与主治医生进行的DSAEK病例术后6个月的最佳眼镜矫正视力(BSCVA)、内皮细胞丢失情况以及术后即刻并发症。该系列代表3名角膜科助手采用与主治医生相同技术完成的最初连续病例。
DSAEK术后,主治医生组的平均BSCVA从20/80提高到20/37,助手组从20/74提高到20/36。两组间内皮细胞丢失无统计学差异(32%对35%)。主治医生组的脱位率为2%,助手组为1%。两组均无原发性移植物失败或瞳孔阻滞病例。
本研究表明,由经验丰富的角膜外科医生或经验不足的助手进行DSAEK术后,视力或内皮细胞丢失无差异。术后并发症也相似。在监督下由新手助手进行的DSAEK的结果和并发症可与经验丰富的DSAEK外科医生相当。