Moraes B N, Bacal F, Teixeira M C T V, Fiorelli A I, Leite P L, Fiorelli L R, Stolf N A G, Bocchi E A
Heart Institute (InCor) of the University of Sao Paulo Medical School, Heart Transplantation Unit, Sao Paulo, Brazil.
Transplant Proc. 2009 Apr;41(3):799-801. doi: 10.1016/j.transproceed.2009.02.043.
Organ transplant shortage is a global problem caused by several factors, most of which are related to members of the family, who play a major role in the donation process.
We sought to determine the most determinant features in the donor profile that relate to positive decisions versus refusal of donation.
Fifty-six families who were approached by the Organ Procurement Organization (OPO) from November 2004 to April 2006 agreed to participate in this work. To assess donor profiles, we used a structured interview.
Parental involvement directly in decisions about donation lead to significantly less frequent consent (P = .005), young donor age was associated with a reduced probability of donation (P = .002), violent death negatively influenced donation consent, excluding suicide (P = .004).
The present study showed violent death, young patient age, and parental donation consent to be the most important factors that make it harder to obtain consent organ donation. When a collateral relative (sibling/uncle) or children were responsible for the donation decision, there was more success of consent.
器官移植短缺是一个由多种因素导致的全球性问题，其中大多数因素与家庭成员有关，他们在捐赠过程中起着主要作用。
我们试图确定捐赠者资料中与同意捐赠或拒绝捐赠的积极决定相关的最具决定性的特征。
2004年11月至2006年4月期间，器官采购组织（OPO）接触的56个家庭同意参与这项工作。为了评估捐赠者资料，我们采用了结构化访谈。
父母直接参与捐赠决策导致同意捐赠的频率显著降低（P = 0.005），年轻的捐赠者年龄与捐赠概率降低相关（P = 0.002），暴力死亡对捐赠同意产生负面影响，但自杀除外（P = 0.004）。
本研究表明，暴力死亡、年轻患者年龄以及父母同意捐赠是使获得器官捐赠同意更加困难的最重要因素。当旁系亲属（兄弟姐妹/叔叔）或子女负责捐赠决策时，同意的成功率更高。
