Park Jong Kwan, Lee Sang Kyi, Han Suk Hee, Kim Sang Deuk, Choi Kyung Soo, Kim Myung Ki
Department of Urology, Institute for Medical Sciences, Chonbuk National University Medical School, Chonju, Korea.
Urology. 2009 Jul;74(1):125-9. doi: 10.1016/j.urology.2008.12.057. Epub 2009 Apr 23.
To compare the effect of warm and room temperature irrigation solution on the incidence of urethral stricture during combined transurethral resection and vaporization of the prostate (CTURVP). Urethral stricture after transurethral surgery of the prostate is a bothersome complication. Warm irrigation improves the blood flow and might decrease the incidence of urethral stricture compared with the use of room temperature irrigation, which decreases the blood flow in the urethral mucosa, resulting in ischemic injury.
The patients who underwent CTURVP were divided into those receiving only room temperature irrigation solution (group 1, 75 patients) or warm irrigation solution with a system maintaining the temperature of the ventral penile skin at about 36 degrees C continuously (group 2, 78 patients). At follow-up, 1, 3, and 6 months later, the International Prostate Symptom Score and peak urine flow rate were evaluated.
The temperature of the ventral penile skin was 20 degrees C and 36 degrees C in groups 1 and 2, respectively. The rate of urethral stricture was 21.3% in group 1 and 6.3% in group 2 at the end of 6 months of follow-up (P = .002).
The results of our study have shown that maintaining the temperature of the urethra with warm irrigation solution during CTURVP probably decreases the incidence of urethral stricture. The temperature in the urethra could be another important factor in stricture formation after CTURVP.
比较温热灌洗液与室温灌洗液在经尿道前列腺联合电切汽化术(CTURVP)中对尿道狭窄发生率的影响。经尿道前列腺手术后的尿道狭窄是一种令人困扰的并发症。与使用室温灌洗液相比,温热灌洗可改善血流,可能降低尿道狭窄的发生率,因为室温灌洗液会减少尿道黏膜的血流,导致缺血性损伤。
将接受CTURVP的患者分为两组,一组仅接受室温灌洗液(第1组,75例患者),另一组接受温热灌洗液,使用一个系统将阴茎腹侧皮肤温度持续维持在约36摄氏度(第2组,78例患者)。在术后1、3和6个月随访时,评估国际前列腺症状评分和最大尿流率。
第1组和第2组阴茎腹侧皮肤温度分别为20摄氏度和36摄氏度。随访6个月结束时,第1组尿道狭窄发生率为21.3%,第2组为6.3%(P = .002)。
我们的研究结果表明,在CTURVP期间使用温热灌洗液维持尿道温度可能会降低尿道狭窄的发生率。尿道温度可能是CTURVP后狭窄形成的另一个重要因素。