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对乙酰氨基酚引起的外阴固定性药疹。

Vulval fixed drug eruption due to paracetamol.

作者信息

Drummond Catherine, Fischer Gayle

机构信息

Department of Dermatology, The Canberra Hospital, Canberra, Australian Capital Territory, Australia.

出版信息

Australas J Dermatol. 2009 May;50(2):118-20. doi: 10.1111/j.1440-0960.2009.00519.x.

Abstract

Paracetamol is a readily available non-prescription analgesic. Fixed drug eruption (FDE) is a well-reported side effect of paracetamol, usually the classic, pigmenting type. In women, it may present as a chronic, erosive vulvitis. We describe a case of FDE due to paracetamol presenting as a chronic erosive vulvitis in an older woman taking multiple medications. Diagnosis was delayed because paracetamol is available without prescription, taken intermittently and may be omitted from the clinical history. Cessation of paracetamol led to prompt resolution of symptoms. Consideration should be given to paracetamol as a cause of FDE presenting as a chronic erosive vulvitis.

摘要

对乙酰氨基酚是一种容易获得的非处方镇痛药。固定性药疹(FDE)是对乙酰氨基酚一种报道较多的副作用,通常为典型的色素沉着型。在女性中,它可能表现为慢性糜烂性外阴炎。我们描述了一例因对乙酰氨基酚导致的固定性药疹,在一位服用多种药物的老年女性中表现为慢性糜烂性外阴炎。诊断延迟是因为对乙酰氨基酚无需处方即可获得,服用是间歇性的,且临床病史中可能未提及。停用对乙酰氨基酚后症状迅速缓解。对于表现为慢性糜烂性外阴炎的固定性药疹,应考虑对乙酰氨基酚为病因。

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