轻躁期双相障碍患者合并症发生率较低。
Lower rates of comorbidities in euthymic bipolar patients.
机构信息
Center for Study and Treatment of Affective Disorders (CETTA), Universidade Federal da Bahia, Salvador-Ba, Brazil.
出版信息
World J Biol Psychiatry. 2009;10(4 Pt 2):474-9. doi: 10.1080/15622970802688929.
OBJECTIVE
This study assessed the frequency of axis I psychiatric comorbidities in euthymic bipolar patients and the clinical differences between patients with and without comorbidities.
METHOD
In this study, 62 euthymic bipolar outpatients assessed using a clinical questionnaire underwent a structured diagnostic interview (SCID/CV-DSM-IV) as well as a symptoms evaluation (YMRS and HAM-D-17).
RESULTS
The lifetime frequency of patients with comorbidities was 27.4%. The most frequent comorbidities were anxiety disorders (33.7%), and the positive associated variables were more advanced age, the presence of a steady partner, a first episode of the depressive type and lifetime attempted suicide.
CONCLUSIONS
The lower frequency of comorbidities found in our study in comparison with those described in the literature may be due to the evaluation restricted only to euthymic patients. This suggests the importance of assessing psychiatric comorbidity in bipolar individuals while not in acute phases of the disorder.
目的
本研究评估了心境稳定的双相情感障碍患者中轴 I 类精神共病的频率，以及伴有和不伴有共病的患者之间的临床差异。
方法
在这项研究中，62 名使用临床问卷评估的心境稳定的双相情感障碍门诊患者接受了结构化诊断访谈（SCID/CV-DSM-IV）以及症状评估（YMRS 和 HAM-D-17）。
结果
患者共病的终身频率为 27.4%。最常见的共病是焦虑障碍（33.7%），阳性相关变量是年龄较大、有稳定的伴侣、首次发作抑郁型和有过自杀未遂史。
结论
与文献中描述的相比，我们的研究中发现的共病频率较低，可能是由于仅对心境稳定的患者进行评估所致。这表明在双相情感障碍患者不处于疾病急性发作期时，评估精神共病的重要性。
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