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前列腺切除术后勃起功能障碍:危险因素评估

Erectile dysfunction after prostatectomy: an evaluation of the risk factors.

作者信息

Soleimani Mohammad, Hosseini Seyyed Yousef, Aliasgari Majid, Dadkhah Farid, Lashay Alireza, Amini Erfan

机构信息

Urology and Nephrology Research Center, Shahid Modarress Medical Center, Shahid Beheshti Medical University, MC, Tehran, IR, Iran.

出版信息

Scand J Urol Nephrol. 2009;43(4):277-81. doi: 10.1080/00365590902930824.

Abstract

OBJECTIVE

The occurrence of erectile dysfunction (ED) in patients who have undergone prostatectomy has been assessed in the previous studies; however, its rate and risk factors vary in different studies. This study was conducted to assess the possible risk factors for ED after prostatectomy.

MATERIAL AND METHODS

In total, 246 men with benign prostatic hyperplasia (BPH) who were candidates for either open prostatectomy or transurethral resection of the prostate (TURP) were admitted in this study during a period of 3 years between December 2000 and December 2003. Cardiac risk index was assessed before the operation using American Heart Association guidelines and erectile function was assessed both preoperatively and 6 months after surgery. Patients with moderate to severe ED according to the five-item version of the International Index of Erectile Function were considered as ED afflicted. In this study, the prevalence of preoperative ED, the incidence of postoperative ED, and those conditions that could lead to an increase in the incidence of postoperative ED in either procedure were determined.

RESULTS

The mean age of the patients was 63.7+/-9.7 years. The prevalence rates of preoperative ED were 24.6% and 25.9% in TURP and open prostatectomy groups, respectively. Among patients with no or mild ED preoperatively, 12.5% showed moderate to severe ED postoperatively (13.4% in TURP group vs 11.25% in open prostatectomy group).

CONCLUSIONS

The incidence rate of postoperative ED after prostatectomy was 12.5%. Risk factors for its appearance included hypertension, diabetes mellitus, higher transfusion rates, higher cardiac risk index and an older age.

摘要

目的

以往研究已对接受前列腺切除术后患者勃起功能障碍(ED)的发生情况进行了评估;然而,不同研究中其发生率和危险因素各不相同。本研究旨在评估前列腺切除术后ED的可能危险因素。

材料与方法

2000年12月至2003年12月的3年间,本研究共纳入246例患有良性前列腺增生(BPH)且拟行开放性前列腺切除术或经尿道前列腺电切术(TURP)的男性患者。术前依据美国心脏协会指南评估心脏风险指数,并在术前及术后6个月评估勃起功能。根据国际勃起功能指数五项版本,将中度至重度ED患者视为患有ED。本研究确定了术前ED的患病率、术后ED的发生率以及在任何一种手术中可能导致术后ED发生率增加的情况。

结果

患者的平均年龄为63.7±9.7岁。TURP组和开放性前列腺切除术组术前ED患病率分别为24.6%和25.9%。术前无或轻度ED的患者中,12.5%术后出现中度至重度ED(TURP组为13.4%,开放性前列腺切除术组为11.25%)。

结论

前列腺切除术后ED的发生率为12.5%。其出现的危险因素包括高血压、糖尿病、较高的输血率、较高的心脏风险指数和高龄。

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