基于直线加速器或机器人图像引导的立体定向放疗治疗孤立淋巴结复发性前列腺癌。
Linac-based or robotic image-guided stereotactic radiotherapy for isolated lymph node recurrent prostate cancer.
机构信息
Department of Radiotherapy, European Institute of Oncology, Milan, Italy.
出版信息
Radiother Oncol. 2009 Oct;93(1):14-7. doi: 10.1016/j.radonc.2009.04.001. Epub 2009 May 4.
We report on 14 patients treated with linac- or robotic image-guided stereotactic radiotherapy for isolated lymph node recurrence from prostate cancer, up to the mean dose of 30Gy/3 fractions. At the mean follow-up of 18.6months, five patients experienced clinical out-field progression. Toxicity was minimal. Further investigation is warranted in order to identify the patients that benefit most from this treatment modality and to define the optimal association of such local approach with androgen deprivation. Hopefully, effective local therapy might reduce the burden of systemic therapies given to the recurrent/metastatic prostate cancer patients.
我们报告了 14 例接受直线加速器或机器人图像引导立体定向放疗治疗前列腺癌孤立淋巴结复发的患者，中位剂量为 30Gy/3 次。在中位随访 18.6 个月时，5 例患者出现临床野外进展。毒性极小。需要进一步研究，以确定哪些患者最受益于这种治疗方式，并确定这种局部治疗方法与雄激素剥夺治疗的最佳联合。希望有效的局部治疗可以减轻复发/转移性前列腺癌患者接受的全身治疗的负担。
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