棘阿米巴角膜炎二十年
Twenty years of acanthamoeba keratitis.
作者信息
Carvalho F R S, Foronda A S, Mannis M J, Höfling-Lima A L, Belfort R, de Freitas Denise
机构信息
Department of Ophthalmology, Federal University of São Paulo-Paulista School of Medicine, Sãu Paulo, Brazil.
出版信息
Cornea. 2009 Jun;28(5):516-9. doi: 10.1097/ICO.0b013e318193e0fe.
PURPOSE
We described the rate of Acanthamoeba keratitis (AK) in a referral eye center in São Paulo, Brazil, through a retrospective review of clinical and laboratorial records of patients over 2 decades.
METHODS
From 1987 to 2006, a total of 581 requests for amoebic laboratory workup in cases of infectious keratitis were investigated. Statistical analyses were applied to analyze a tendency of AK cases.
RESULTS
Acanthamoeba species were cultured from corneal scrapings of 185 patients, 5 of them with bilateral infection. Eighty-three percent of those patients were related with contact lens wear.
CONCLUSIONS
The results suggested that patients with AK have persisted and increased over time at our ophthalmology center. Contact lenses showed to be a potential risk factor. Amoebic corneal infection can be considered as a new but well-established disease in Brazilian ophthalmology and visual sciences.
目的
通过对20多年来患者的临床和实验室记录进行回顾性分析，我们描述了巴西圣保罗一家转诊眼科中心的棘阿米巴角膜炎（AK）发病率。
方法
对1987年至2006年期间因感染性角膜炎进行阿米巴实验室检查的581例病例申请进行了调查。应用统计分析方法分析AK病例的趋势。
结果
从185例患者的角膜刮片中培养出棘阿米巴属，其中5例为双侧感染。这些患者中有83%与佩戴隐形眼镜有关。
结论
结果表明，在我们的眼科中心，AK患者的数量一直存在且随时间增加。隐形眼镜被证明是一个潜在的危险因素。在巴西眼科和视觉科学领域，阿米巴角膜感染可被视为一种新的但已被充分认识的疾病。
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